Abstract
Purpose To investigate the prevalence, awareness, and risk factors for primary open-angle glaucoma (POAG) in the Korean population. Design The Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. Participants A total of 13 831 participants 40 years of age or older were included from the KNHANES database for the years 2008 through 2011. Methods Glaucoma diagnosis was based on the International Society of Geographical and Epidemiological Ophthalmology criteria. The prevalence of POAG and the proportion of POAG patients previously informed of the disease were calculated using KNHANES sample weights. Ocular and systemic factors were compared between the POAG and control groups. Univariate and multivariate logistic regression analyses were used to evaluate the risk factors for POAG. Main Outcome Measures Weighted prevalence, awareness, and risk factors for POAG. Results The prevalence of POAG in the Korean population was 4.7% (95% confidence interval, 4.2-5.1): 5.5% in men and 3.9% in women, respectively, which increased with age (P < 0.001). The mean intraocular pressure (IOP) in POAG eyes was 15.0±0.4 mmHg, which was higher than that of the control group (14.0±0.1 mmHg; P < 0.001). Multivariate logistic regression analysis revealed that older age (P < 0.001), male gender (P < 0.001), higher IOP (P < 0.001), myopia (P < 0.001), hypertension (P = 0.031), and nonoverweight status (P = 0.017) were associated significantly with POAG in the Korean population. Among the 710 study participants diagnosed with POAG, only 8.0% were aware of the disease. Conclusions This was the first study to examine the prevalence, awareness, and risk factors of POAG in the Korean population using 4-year KNHANES data. Koreans with higher IOP, myopia, older age, male gender, hypertension, and nonoverweight status require more attention and support from the glaucoma screening and surveillance systems.
| Original language | English |
|---|---|
| Pages (from-to) | 532-541 |
| Number of pages | 10 |
| Journal | Ophthalmology |
| Volume | 123 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2016 Mar 1 |
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All Science Journal Classification (ASJC) codes
- Ophthalmology
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Prevalence, awareness, and risk factors of primary open-angle glaucoma Korea National Health and Nutrition Examination Survey 2008-2011. / Kim, Ko Eun; Kim, Moon Jung; Park, Ki Ho; Jeoung, Jin Wook; Kim, Seok Hwan; Kim, Chan Yun; Kang, Se Woong.
In: Ophthalmology, Vol. 123, No. 3, 01.03.2016, p. 532-541.Research output: Contribution to journal › Article
TY - JOUR
T1 - Prevalence, awareness, and risk factors of primary open-angle glaucoma Korea National Health and Nutrition Examination Survey 2008-2011
AU - Kim, Ko Eun
AU - Kim, Moon Jung
AU - Park, Ki Ho
AU - Jeoung, Jin Wook
AU - Kim, Seok Hwan
AU - Kim, Chan Yun
AU - Kang, Se Woong
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Purpose To investigate the prevalence, awareness, and risk factors for primary open-angle glaucoma (POAG) in the Korean population. Design The Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. Participants A total of 13 831 participants 40 years of age or older were included from the KNHANES database for the years 2008 through 2011. Methods Glaucoma diagnosis was based on the International Society of Geographical and Epidemiological Ophthalmology criteria. The prevalence of POAG and the proportion of POAG patients previously informed of the disease were calculated using KNHANES sample weights. Ocular and systemic factors were compared between the POAG and control groups. Univariate and multivariate logistic regression analyses were used to evaluate the risk factors for POAG. Main Outcome Measures Weighted prevalence, awareness, and risk factors for POAG. Results The prevalence of POAG in the Korean population was 4.7% (95% confidence interval, 4.2-5.1): 5.5% in men and 3.9% in women, respectively, which increased with age (P < 0.001). The mean intraocular pressure (IOP) in POAG eyes was 15.0±0.4 mmHg, which was higher than that of the control group (14.0±0.1 mmHg; P < 0.001). Multivariate logistic regression analysis revealed that older age (P < 0.001), male gender (P < 0.001), higher IOP (P < 0.001), myopia (P < 0.001), hypertension (P = 0.031), and nonoverweight status (P = 0.017) were associated significantly with POAG in the Korean population. Among the 710 study participants diagnosed with POAG, only 8.0% were aware of the disease. Conclusions This was the first study to examine the prevalence, awareness, and risk factors of POAG in the Korean population using 4-year KNHANES data. Koreans with higher IOP, myopia, older age, male gender, hypertension, and nonoverweight status require more attention and support from the glaucoma screening and surveillance systems.
AB - Purpose To investigate the prevalence, awareness, and risk factors for primary open-angle glaucoma (POAG) in the Korean population. Design The Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. Participants A total of 13 831 participants 40 years of age or older were included from the KNHANES database for the years 2008 through 2011. Methods Glaucoma diagnosis was based on the International Society of Geographical and Epidemiological Ophthalmology criteria. The prevalence of POAG and the proportion of POAG patients previously informed of the disease were calculated using KNHANES sample weights. Ocular and systemic factors were compared between the POAG and control groups. Univariate and multivariate logistic regression analyses were used to evaluate the risk factors for POAG. Main Outcome Measures Weighted prevalence, awareness, and risk factors for POAG. Results The prevalence of POAG in the Korean population was 4.7% (95% confidence interval, 4.2-5.1): 5.5% in men and 3.9% in women, respectively, which increased with age (P < 0.001). The mean intraocular pressure (IOP) in POAG eyes was 15.0±0.4 mmHg, which was higher than that of the control group (14.0±0.1 mmHg; P < 0.001). Multivariate logistic regression analysis revealed that older age (P < 0.001), male gender (P < 0.001), higher IOP (P < 0.001), myopia (P < 0.001), hypertension (P = 0.031), and nonoverweight status (P = 0.017) were associated significantly with POAG in the Korean population. Among the 710 study participants diagnosed with POAG, only 8.0% were aware of the disease. Conclusions This was the first study to examine the prevalence, awareness, and risk factors of POAG in the Korean population using 4-year KNHANES data. Koreans with higher IOP, myopia, older age, male gender, hypertension, and nonoverweight status require more attention and support from the glaucoma screening and surveillance systems.
UR - http://www.scopus.com/inward/record.url?scp=84959275168&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959275168&partnerID=8YFLogxK
U2 - 10.1016/j.ophtha.2015.11.004
DO - 10.1016/j.ophtha.2015.11.004
M3 - Article
C2 - 26746594
AN - SCOPUS:84959275168
VL - 123
SP - 532
EP - 541
JO - Ophthalmology
JF - Ophthalmology
SN - 0161-6420
IS - 3
ER -