Prevalence, awareness, and risk factors of primary open-angle glaucoma Korea National Health and Nutrition Examination Survey 2008-2011

Ko Eun Kim, Moon Jung Kim, Ki Ho Park, Jin Wook Jeoung, Seok Hwan Kim, Chan Yun Kim, Se Woong Kang

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Purpose To investigate the prevalence, awareness, and risk factors for primary open-angle glaucoma (POAG) in the Korean population. Design The Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. Participants A total of 13 831 participants 40 years of age or older were included from the KNHANES database for the years 2008 through 2011. Methods Glaucoma diagnosis was based on the International Society of Geographical and Epidemiological Ophthalmology criteria. The prevalence of POAG and the proportion of POAG patients previously informed of the disease were calculated using KNHANES sample weights. Ocular and systemic factors were compared between the POAG and control groups. Univariate and multivariate logistic regression analyses were used to evaluate the risk factors for POAG. Main Outcome Measures Weighted prevalence, awareness, and risk factors for POAG. Results The prevalence of POAG in the Korean population was 4.7% (95% confidence interval, 4.2-5.1): 5.5% in men and 3.9% in women, respectively, which increased with age (P < 0.001). The mean intraocular pressure (IOP) in POAG eyes was 15.0±0.4 mmHg, which was higher than that of the control group (14.0±0.1 mmHg; P < 0.001). Multivariate logistic regression analysis revealed that older age (P < 0.001), male gender (P < 0.001), higher IOP (P < 0.001), myopia (P < 0.001), hypertension (P = 0.031), and nonoverweight status (P = 0.017) were associated significantly with POAG in the Korean population. Among the 710 study participants diagnosed with POAG, only 8.0% were aware of the disease. Conclusions This was the first study to examine the prevalence, awareness, and risk factors of POAG in the Korean population using 4-year KNHANES data. Koreans with higher IOP, myopia, older age, male gender, hypertension, and nonoverweight status require more attention and support from the glaucoma screening and surveillance systems.

Original languageEnglish
Pages (from-to)532-541
Number of pages10
JournalOphthalmology
Volume123
Issue number3
DOIs
Publication statusPublished - 2016 Mar 1

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Nutrition Surveys
Korea
Intraocular Pressure
Population
Myopia
Glaucoma
Primary Open Angle Glaucoma
Logistic Models
Regression Analysis
Hypertension
Control Groups
Ophthalmology
Cross-Sectional Studies
Outcome Assessment (Health Care)
Databases
Confidence Intervals
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Kim, Ko Eun ; Kim, Moon Jung ; Park, Ki Ho ; Jeoung, Jin Wook ; Kim, Seok Hwan ; Kim, Chan Yun ; Kang, Se Woong. / Prevalence, awareness, and risk factors of primary open-angle glaucoma Korea National Health and Nutrition Examination Survey 2008-2011. In: Ophthalmology. 2016 ; Vol. 123, No. 3. pp. 532-541.
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abstract = "Purpose To investigate the prevalence, awareness, and risk factors for primary open-angle glaucoma (POAG) in the Korean population. Design The Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. Participants A total of 13 831 participants 40 years of age or older were included from the KNHANES database for the years 2008 through 2011. Methods Glaucoma diagnosis was based on the International Society of Geographical and Epidemiological Ophthalmology criteria. The prevalence of POAG and the proportion of POAG patients previously informed of the disease were calculated using KNHANES sample weights. Ocular and systemic factors were compared between the POAG and control groups. Univariate and multivariate logistic regression analyses were used to evaluate the risk factors for POAG. Main Outcome Measures Weighted prevalence, awareness, and risk factors for POAG. Results The prevalence of POAG in the Korean population was 4.7{\%} (95{\%} confidence interval, 4.2-5.1): 5.5{\%} in men and 3.9{\%} in women, respectively, which increased with age (P < 0.001). The mean intraocular pressure (IOP) in POAG eyes was 15.0±0.4 mmHg, which was higher than that of the control group (14.0±0.1 mmHg; P < 0.001). Multivariate logistic regression analysis revealed that older age (P < 0.001), male gender (P < 0.001), higher IOP (P < 0.001), myopia (P < 0.001), hypertension (P = 0.031), and nonoverweight status (P = 0.017) were associated significantly with POAG in the Korean population. Among the 710 study participants diagnosed with POAG, only 8.0{\%} were aware of the disease. Conclusions This was the first study to examine the prevalence, awareness, and risk factors of POAG in the Korean population using 4-year KNHANES data. Koreans with higher IOP, myopia, older age, male gender, hypertension, and nonoverweight status require more attention and support from the glaucoma screening and surveillance systems.",
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Prevalence, awareness, and risk factors of primary open-angle glaucoma Korea National Health and Nutrition Examination Survey 2008-2011. / Kim, Ko Eun; Kim, Moon Jung; Park, Ki Ho; Jeoung, Jin Wook; Kim, Seok Hwan; Kim, Chan Yun; Kang, Se Woong.

In: Ophthalmology, Vol. 123, No. 3, 01.03.2016, p. 532-541.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Prevalence, awareness, and risk factors of primary open-angle glaucoma Korea National Health and Nutrition Examination Survey 2008-2011

AU - Kim, Ko Eun

AU - Kim, Moon Jung

AU - Park, Ki Ho

AU - Jeoung, Jin Wook

AU - Kim, Seok Hwan

AU - Kim, Chan Yun

AU - Kang, Se Woong

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Purpose To investigate the prevalence, awareness, and risk factors for primary open-angle glaucoma (POAG) in the Korean population. Design The Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. Participants A total of 13 831 participants 40 years of age or older were included from the KNHANES database for the years 2008 through 2011. Methods Glaucoma diagnosis was based on the International Society of Geographical and Epidemiological Ophthalmology criteria. The prevalence of POAG and the proportion of POAG patients previously informed of the disease were calculated using KNHANES sample weights. Ocular and systemic factors were compared between the POAG and control groups. Univariate and multivariate logistic regression analyses were used to evaluate the risk factors for POAG. Main Outcome Measures Weighted prevalence, awareness, and risk factors for POAG. Results The prevalence of POAG in the Korean population was 4.7% (95% confidence interval, 4.2-5.1): 5.5% in men and 3.9% in women, respectively, which increased with age (P < 0.001). The mean intraocular pressure (IOP) in POAG eyes was 15.0±0.4 mmHg, which was higher than that of the control group (14.0±0.1 mmHg; P < 0.001). Multivariate logistic regression analysis revealed that older age (P < 0.001), male gender (P < 0.001), higher IOP (P < 0.001), myopia (P < 0.001), hypertension (P = 0.031), and nonoverweight status (P = 0.017) were associated significantly with POAG in the Korean population. Among the 710 study participants diagnosed with POAG, only 8.0% were aware of the disease. Conclusions This was the first study to examine the prevalence, awareness, and risk factors of POAG in the Korean population using 4-year KNHANES data. Koreans with higher IOP, myopia, older age, male gender, hypertension, and nonoverweight status require more attention and support from the glaucoma screening and surveillance systems.

AB - Purpose To investigate the prevalence, awareness, and risk factors for primary open-angle glaucoma (POAG) in the Korean population. Design The Korea National Health and Nutrition Examination Survey (KNHANES), a population-based cross-sectional study using a complex, stratified, multistage, probability-cluster survey. Participants A total of 13 831 participants 40 years of age or older were included from the KNHANES database for the years 2008 through 2011. Methods Glaucoma diagnosis was based on the International Society of Geographical and Epidemiological Ophthalmology criteria. The prevalence of POAG and the proportion of POAG patients previously informed of the disease were calculated using KNHANES sample weights. Ocular and systemic factors were compared between the POAG and control groups. Univariate and multivariate logistic regression analyses were used to evaluate the risk factors for POAG. Main Outcome Measures Weighted prevalence, awareness, and risk factors for POAG. Results The prevalence of POAG in the Korean population was 4.7% (95% confidence interval, 4.2-5.1): 5.5% in men and 3.9% in women, respectively, which increased with age (P < 0.001). The mean intraocular pressure (IOP) in POAG eyes was 15.0±0.4 mmHg, which was higher than that of the control group (14.0±0.1 mmHg; P < 0.001). Multivariate logistic regression analysis revealed that older age (P < 0.001), male gender (P < 0.001), higher IOP (P < 0.001), myopia (P < 0.001), hypertension (P = 0.031), and nonoverweight status (P = 0.017) were associated significantly with POAG in the Korean population. Among the 710 study participants diagnosed with POAG, only 8.0% were aware of the disease. Conclusions This was the first study to examine the prevalence, awareness, and risk factors of POAG in the Korean population using 4-year KNHANES data. Koreans with higher IOP, myopia, older age, male gender, hypertension, and nonoverweight status require more attention and support from the glaucoma screening and surveillance systems.

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