Prevalence of antibodies to borrelia burgdorferi, the lyme disease agent, among residents in youngdong area of the kangwon province

Sangnae Cho, J. D. Kim, Y. Chong, Mingeol Lee, J. B. Lee, E. W. Ahn

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

As an attempt to find a serological evidence of Lyme disease, this study was initiated to determine the prevalence of antibodies to Borrelia burgdorferi among residents throughout the Youngdong area of the Kangwon province where Ixodes persulcatus, a suspected vector, had been identified. An enzyme-linked immunosorbent assay (ELISA) was employed to detect antibodies to the organisms. For the controls, 200 employees in a general hospital in Seoul area were examined by ELISA. The criteria for the seroreactivity was determined by adding 3 x s.d. to the mean absorbance of the controls. Of 200 controls examined, 3 (1.5%) were seroreactive. On the other hand, 9 (4.6%) of 197 residents from Youngdong area who were visiting the Kangneung Medical Center were seroreactive to B. burgdorferi. Of interest was to note that among 155 patients with febrile illness whose serum specimens were submitted for the test for leptospirosis, 18 (11.6%) were seroreactive to B. burgdorferi. Among all of the seroreactive specimens, six (20.0%) were reactive to Leptospira interrogans serovar lai in ELISA or to Treponema pallidum by a specific hemagglutination test. This study thus suggested that there may be an evidence of the infection by B. burgdorferi or its closely related organisms. The question whether Lyme disease is present in Korea or not, however, remains to be confirmed clinically and bacteriologically.

Original languageEnglish
Pages (from-to)163-170
Number of pages8
JournalJournal of the Korean Society for Microbiology
Volume25
Issue number2
Publication statusPublished - 1990 Oct 3

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Borrelia burgdorferi
Lyme Disease
Antibodies
Enzyme-Linked Immunosorbent Assay
Leptospira interrogans
Treponema pallidum
Hemagglutination Tests
Ixodes
Leptospirosis
Korea
General Hospitals
Fever
Infection
Serum

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Microbiology

Cite this

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title = "Prevalence of antibodies to borrelia burgdorferi, the lyme disease agent, among residents in youngdong area of the kangwon province",
abstract = "As an attempt to find a serological evidence of Lyme disease, this study was initiated to determine the prevalence of antibodies to Borrelia burgdorferi among residents throughout the Youngdong area of the Kangwon province where Ixodes persulcatus, a suspected vector, had been identified. An enzyme-linked immunosorbent assay (ELISA) was employed to detect antibodies to the organisms. For the controls, 200 employees in a general hospital in Seoul area were examined by ELISA. The criteria for the seroreactivity was determined by adding 3 x s.d. to the mean absorbance of the controls. Of 200 controls examined, 3 (1.5{\%}) were seroreactive. On the other hand, 9 (4.6{\%}) of 197 residents from Youngdong area who were visiting the Kangneung Medical Center were seroreactive to B. burgdorferi. Of interest was to note that among 155 patients with febrile illness whose serum specimens were submitted for the test for leptospirosis, 18 (11.6{\%}) were seroreactive to B. burgdorferi. Among all of the seroreactive specimens, six (20.0{\%}) were reactive to Leptospira interrogans serovar lai in ELISA or to Treponema pallidum by a specific hemagglutination test. This study thus suggested that there may be an evidence of the infection by B. burgdorferi or its closely related organisms. The question whether Lyme disease is present in Korea or not, however, remains to be confirmed clinically and bacteriologically.",
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Prevalence of antibodies to borrelia burgdorferi, the lyme disease agent, among residents in youngdong area of the kangwon province. / Cho, Sangnae; Kim, J. D.; Chong, Y.; Lee, Mingeol; Lee, J. B.; Ahn, E. W.

In: Journal of the Korean Society for Microbiology, Vol. 25, No. 2, 03.10.1990, p. 163-170.

Research output: Contribution to journalArticle

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