As an attempt to find a serological evidence of Lyme disease, this study was initiated to determine the prevalence of antibodies to Borrelia burgdorferi among residents throughout the Youngdong area of the Kangwon province where Ixodes persulcatus, a suspected vector, had been identified. An enzyme-linked immunosorbent assay (ELISA) was employed to detect antibodies to the organisms. For the controls, 200 employees in a general hospital in Seoul area were examined by ELISA. The criteria for the seroreactivity was determined by adding 3 x s.d. to the mean absorbance of the controls. Of 200 controls examined, 3 (1.5%) were seroreactive. On the other hand, 9 (4.6%) of 197 residents from Youngdong area who were visiting the Kangneung Medical Center were seroreactive to B. burgdorferi. Of interest was to note that among 155 patients with febrile illness whose serum specimens were submitted for the test for leptospirosis, 18 (11.6%) were seroreactive to B. burgdorferi. Among all of the seroreactive specimens, six (20.0%) were reactive to Leptospira interrogans serovar lai in ELISA or to Treponema pallidum by a specific hemagglutination test. This study thus suggested that there may be an evidence of the infection by B. burgdorferi or its closely related organisms. The question whether Lyme disease is present in Korea or not, however, remains to be confirmed clinically and bacteriologically.
|Number of pages||8|
|Journal||Journal of the Korean Society for Microbiology|
|Publication status||Published - 1990|
All Science Journal Classification (ASJC) codes
- Microbiology (medical)