Prevalence of antibodies to Legionella pneumophila in animal populations

M. T. Collins, S. N. Cho, J. S. Reif

Research output: Contribution to journalArticle

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Abstract

We examined more than 2,800 human and animal sera for antibodies to four serogroups of Legionella pneumophila by using the microagglutination test. Antibody titers of ≥1:64 were considered positive. The occurrence of positive equine sera (31.4%) was significantly higher than the occurrence of positive sera in cattle (5.1%), swine (2.9%), sheep (1.9%), dogs (1.9%), goats (0.5%), wildlife (0%), and humans (0.4%). The highest titer measured in horses was 1:512. The occurrence of positive sera in horses was related directly to age. In horses ≤1,2 to 3, 4 to 7, 8 to 12, and ≥13 years old,the percentages of positive sera were 0, 10.1, 30.3, 4.9 and 58.1%, respectively. When we compared age-specific serogroup-specific rates in horses from Colorado and Pennsylvania, we found differences. With horses 8 to 12 and ≥13 years old, there was a significantly higher (P<0.05) occurrence of sera that reacted to serogroups II and III in horses from Pennsylvania. Of 242 positive sera, 43.8% reacted to a single serogroup (serogroup III or I most commonly), and 56.2% reacted to multiple serogroups (serogroups II and III or serogroups I, II, and III most commonly). A high percentage of seropositive horses suggested that horses are commonly infected with L. pneumophila or related organisms, and the age-specific rates of occurrence indicate that infection was related directly to duration of exposure. A definitive demonstration of equinine infection will depend on isolation of the agent and repetition of this serological study with antigens obtained from organisms isolated from horses.

Original languageEnglish
Pages (from-to)130-136
Number of pages7
JournalJournal of Clinical Microbiology
Volume15
Issue number1
Publication statusPublished - 1982 Jan 1

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Legionella pneumophila
Horses
Antibodies
Population
Serum
Serogroup
Infection
Goats
Sheep
Swine
Dogs
Antigens

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

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title = "Prevalence of antibodies to Legionella pneumophila in animal populations",
abstract = "We examined more than 2,800 human and animal sera for antibodies to four serogroups of Legionella pneumophila by using the microagglutination test. Antibody titers of ≥1:64 were considered positive. The occurrence of positive equine sera (31.4{\%}) was significantly higher than the occurrence of positive sera in cattle (5.1{\%}), swine (2.9{\%}), sheep (1.9{\%}), dogs (1.9{\%}), goats (0.5{\%}), wildlife (0{\%}), and humans (0.4{\%}). The highest titer measured in horses was 1:512. The occurrence of positive sera in horses was related directly to age. In horses ≤1,2 to 3, 4 to 7, 8 to 12, and ≥13 years old,the percentages of positive sera were 0, 10.1, 30.3, 4.9 and 58.1{\%}, respectively. When we compared age-specific serogroup-specific rates in horses from Colorado and Pennsylvania, we found differences. With horses 8 to 12 and ≥13 years old, there was a significantly higher (P<0.05) occurrence of sera that reacted to serogroups II and III in horses from Pennsylvania. Of 242 positive sera, 43.8{\%} reacted to a single serogroup (serogroup III or I most commonly), and 56.2{\%} reacted to multiple serogroups (serogroups II and III or serogroups I, II, and III most commonly). A high percentage of seropositive horses suggested that horses are commonly infected with L. pneumophila or related organisms, and the age-specific rates of occurrence indicate that infection was related directly to duration of exposure. A definitive demonstration of equinine infection will depend on isolation of the agent and repetition of this serological study with antigens obtained from organisms isolated from horses.",
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Prevalence of antibodies to Legionella pneumophila in animal populations. / Collins, M. T.; Cho, S. N.; Reif, J. S.

In: Journal of Clinical Microbiology, Vol. 15, No. 1, 01.01.1982, p. 130-136.

Research output: Contribution to journalArticle

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