Prevalence of breast cancer-related risk factors in underweight premenopausal women: the Korea National Health and Nutrition Examination Survey IV–VI

Joo Heung Kim, Kwang Hyun Yoon, Ho Hur, Seho Park, Jee Ye Kim, Hyung Seok Park, Seung Ii Kim, Young Up Cho, Byeong Woo Park

Research output: Contribution to journalArticle

Abstract

Purpose: This study aimed to examine the prevalence and trends of breast cancer-related risk factors and characteristics in premenopausal underweight Korean women according to birth year cohort. Methods: Socioeconomic and breast cancer-related risk factors were investigated in 13,415 premenopausal women using nationwide cross-sectional surveys performed between 2007 and 2015. Underweight was defined as body mass index < 18.5 kg/m 2 . Multivariable models were created using complex sample procedures. Results: Underweight women comprised 9.5% of the sample. Compared with those who were obese or of normal weight, underweight women were characterized by younger age, higher rate of metropolitan residence, higher economic status, more education, higher rates of non-manual employment and unmarried status, lower rate of early menarche, higher rates of nulliparity, lower parity, alcohol consumption, and never having breastfed, and lower levels of high physical activity. Multivariable analysis showed that underweight women had a significantly lower rate of early menarche, lower parity, higher nulliparity, older age at first delivery, and lower levels of high physical activity compared to premenopausal women with normal weight. These trends were more apparent among women born in recent years. Conclusions: Underweight Korean premenopausal women exhibit distinctive features associated with an increased risk of breast cancer, except for a lower rate of early menarche. These associations were prominent in recent generations. Assessment of the association between underweight and premenopausal breast cancer risk should focus on promoting healthy lifestyles to reduce breast cancer risk.

Original languageEnglish
Pages (from-to)515-524
Number of pages10
JournalBreast Cancer Research and Treatment
Volume174
Issue number2
DOIs
Publication statusPublished - 2019 Apr 15

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Thinness
Nutrition Surveys
Korea
Breast Neoplasms
Parity
Menarche
Exercise
Weights and Measures
Alcohol Drinking
Body Mass Index
Cross-Sectional Studies
Economics
Parturition
Education

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Kim, Joo Heung ; Yoon, Kwang Hyun ; Hur, Ho ; Park, Seho ; Kim, Jee Ye ; Park, Hyung Seok ; Kim, Seung Ii ; Cho, Young Up ; Park, Byeong Woo. / Prevalence of breast cancer-related risk factors in underweight premenopausal women : the Korea National Health and Nutrition Examination Survey IV–VI. In: Breast Cancer Research and Treatment. 2019 ; Vol. 174, No. 2. pp. 515-524.
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abstract = "Purpose: This study aimed to examine the prevalence and trends of breast cancer-related risk factors and characteristics in premenopausal underweight Korean women according to birth year cohort. Methods: Socioeconomic and breast cancer-related risk factors were investigated in 13,415 premenopausal women using nationwide cross-sectional surveys performed between 2007 and 2015. Underweight was defined as body mass index < 18.5 kg/m 2 . Multivariable models were created using complex sample procedures. Results: Underweight women comprised 9.5{\%} of the sample. Compared with those who were obese or of normal weight, underweight women were characterized by younger age, higher rate of metropolitan residence, higher economic status, more education, higher rates of non-manual employment and unmarried status, lower rate of early menarche, higher rates of nulliparity, lower parity, alcohol consumption, and never having breastfed, and lower levels of high physical activity. Multivariable analysis showed that underweight women had a significantly lower rate of early menarche, lower parity, higher nulliparity, older age at first delivery, and lower levels of high physical activity compared to premenopausal women with normal weight. These trends were more apparent among women born in recent years. Conclusions: Underweight Korean premenopausal women exhibit distinctive features associated with an increased risk of breast cancer, except for a lower rate of early menarche. These associations were prominent in recent generations. Assessment of the association between underweight and premenopausal breast cancer risk should focus on promoting healthy lifestyles to reduce breast cancer risk.",
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Prevalence of breast cancer-related risk factors in underweight premenopausal women : the Korea National Health and Nutrition Examination Survey IV–VI. / Kim, Joo Heung; Yoon, Kwang Hyun; Hur, Ho; Park, Seho; Kim, Jee Ye; Park, Hyung Seok; Kim, Seung Ii; Cho, Young Up; Park, Byeong Woo.

In: Breast Cancer Research and Treatment, Vol. 174, No. 2, 15.04.2019, p. 515-524.

Research output: Contribution to journalArticle

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T1 - Prevalence of breast cancer-related risk factors in underweight premenopausal women

T2 - the Korea National Health and Nutrition Examination Survey IV–VI

AU - Kim, Joo Heung

AU - Yoon, Kwang Hyun

AU - Hur, Ho

AU - Park, Seho

AU - Kim, Jee Ye

AU - Park, Hyung Seok

AU - Kim, Seung Ii

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AU - Park, Byeong Woo

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N2 - Purpose: This study aimed to examine the prevalence and trends of breast cancer-related risk factors and characteristics in premenopausal underweight Korean women according to birth year cohort. Methods: Socioeconomic and breast cancer-related risk factors were investigated in 13,415 premenopausal women using nationwide cross-sectional surveys performed between 2007 and 2015. Underweight was defined as body mass index < 18.5 kg/m 2 . Multivariable models were created using complex sample procedures. Results: Underweight women comprised 9.5% of the sample. Compared with those who were obese or of normal weight, underweight women were characterized by younger age, higher rate of metropolitan residence, higher economic status, more education, higher rates of non-manual employment and unmarried status, lower rate of early menarche, higher rates of nulliparity, lower parity, alcohol consumption, and never having breastfed, and lower levels of high physical activity. Multivariable analysis showed that underweight women had a significantly lower rate of early menarche, lower parity, higher nulliparity, older age at first delivery, and lower levels of high physical activity compared to premenopausal women with normal weight. These trends were more apparent among women born in recent years. Conclusions: Underweight Korean premenopausal women exhibit distinctive features associated with an increased risk of breast cancer, except for a lower rate of early menarche. These associations were prominent in recent generations. Assessment of the association between underweight and premenopausal breast cancer risk should focus on promoting healthy lifestyles to reduce breast cancer risk.

AB - Purpose: This study aimed to examine the prevalence and trends of breast cancer-related risk factors and characteristics in premenopausal underweight Korean women according to birth year cohort. Methods: Socioeconomic and breast cancer-related risk factors were investigated in 13,415 premenopausal women using nationwide cross-sectional surveys performed between 2007 and 2015. Underweight was defined as body mass index < 18.5 kg/m 2 . Multivariable models were created using complex sample procedures. Results: Underweight women comprised 9.5% of the sample. Compared with those who were obese or of normal weight, underweight women were characterized by younger age, higher rate of metropolitan residence, higher economic status, more education, higher rates of non-manual employment and unmarried status, lower rate of early menarche, higher rates of nulliparity, lower parity, alcohol consumption, and never having breastfed, and lower levels of high physical activity. Multivariable analysis showed that underweight women had a significantly lower rate of early menarche, lower parity, higher nulliparity, older age at first delivery, and lower levels of high physical activity compared to premenopausal women with normal weight. These trends were more apparent among women born in recent years. Conclusions: Underweight Korean premenopausal women exhibit distinctive features associated with an increased risk of breast cancer, except for a lower rate of early menarche. These associations were prominent in recent generations. Assessment of the association between underweight and premenopausal breast cancer risk should focus on promoting healthy lifestyles to reduce breast cancer risk.

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