Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men

Jae Sun Uhm, Il Ung Hwang, Yong Seog Oh, Min Seok Choi, Sung Won Jang, Woo Seung Shin, Ji Hoon Kim, Man Young Lee, Tai Ho Rho, You Ho Kim, Jung Hoon Sung, Young Soo Lee, Jeong Gwan Cho, Dong Jin Oh, Dae Kyeong Kim, June Namgung, Kyoung Min Park, Yong Hoon Kim, Yoon Nyun Kim, Hong Euy LimTae Joon Cha, Young Keun On, Dong Gu Shin, Hui Nam Pak, Nam Ho Kim

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background: The objective of this study was to determine the prevalence of electrocardiographic (ECG) findings suggestive of sudden cardiac death risk in apparently healthy young Korean men. Methods: We administered questionnaires that elicited personal and family histories and performed ECGs on 10,867 male subjects (mean age, 20.9 years). The subjects with abnormal ECG findings underwent echocardiography, a treadmill test, Holter monitoring, a flecainide provocation test, or an electrophysiologic study (EPS) according to the ECG findings and histories. Results: Of the subjects, 5.95% had left ventricular hypertrophy on ECG, but no subjects had hypertrophic cardiomyopathy by echocardiography. The percentage of subjects with a Brugada ECG pattern was 0.90%. We identified one subject with a positive result on the flecainide provocation test. The percentage of subjects with a preexcitation ECG was 0.17%. In two of the subjects, supraventricular tachycardia was induced in the EPS. Of the subjects, 0.05% had epsilon waves, but there were no subjects with arrhythmogenic right ventricular dysplasia/cardiomyopathy by echocardiography. The percentage of subjects with long QT intervals was 0.02%, but there were no arrhythmias on the treadmill test or Holter monitoring. Conclusions: The prevalence of a Brugada ECG pattern in apparently healthy young men is higher in Korea than other countries.

Original languageEnglish
Pages (from-to)717-723
Number of pages7
JournalPACE - Pacing and Clinical Electrophysiology
Volume34
Issue number6
DOIs
Publication statusPublished - 2011 Jun 1

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Sudden Cardiac Death
Flecainide
Echocardiography
Ambulatory Electrocardiography
Exercise Test
Arrhythmogenic Right Ventricular Dysplasia
Supraventricular Tachycardia
Hypertrophic Cardiomyopathy
Left Ventricular Hypertrophy
Korea
Cardiac Arrhythmias
Electrocardiography

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Uhm, Jae Sun ; Hwang, Il Ung ; Oh, Yong Seog ; Choi, Min Seok ; Jang, Sung Won ; Shin, Woo Seung ; Kim, Ji Hoon ; Lee, Man Young ; Rho, Tai Ho ; Kim, You Ho ; Sung, Jung Hoon ; Lee, Young Soo ; Cho, Jeong Gwan ; Oh, Dong Jin ; Kim, Dae Kyeong ; Namgung, June ; Park, Kyoung Min ; Kim, Yong Hoon ; Kim, Yoon Nyun ; Lim, Hong Euy ; Cha, Tae Joon ; On, Young Keun ; Shin, Dong Gu ; Pak, Hui Nam ; Kim, Nam Ho. / Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men. In: PACE - Pacing and Clinical Electrophysiology. 2011 ; Vol. 34, No. 6. pp. 717-723.
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title = "Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men",
abstract = "Background: The objective of this study was to determine the prevalence of electrocardiographic (ECG) findings suggestive of sudden cardiac death risk in apparently healthy young Korean men. Methods: We administered questionnaires that elicited personal and family histories and performed ECGs on 10,867 male subjects (mean age, 20.9 years). The subjects with abnormal ECG findings underwent echocardiography, a treadmill test, Holter monitoring, a flecainide provocation test, or an electrophysiologic study (EPS) according to the ECG findings and histories. Results: Of the subjects, 5.95{\%} had left ventricular hypertrophy on ECG, but no subjects had hypertrophic cardiomyopathy by echocardiography. The percentage of subjects with a Brugada ECG pattern was 0.90{\%}. We identified one subject with a positive result on the flecainide provocation test. The percentage of subjects with a preexcitation ECG was 0.17{\%}. In two of the subjects, supraventricular tachycardia was induced in the EPS. Of the subjects, 0.05{\%} had epsilon waves, but there were no subjects with arrhythmogenic right ventricular dysplasia/cardiomyopathy by echocardiography. The percentage of subjects with long QT intervals was 0.02{\%}, but there were no arrhythmias on the treadmill test or Holter monitoring. Conclusions: The prevalence of a Brugada ECG pattern in apparently healthy young men is higher in Korea than other countries.",
author = "Uhm, {Jae Sun} and Hwang, {Il Ung} and Oh, {Yong Seog} and Choi, {Min Seok} and Jang, {Sung Won} and Shin, {Woo Seung} and Kim, {Ji Hoon} and Lee, {Man Young} and Rho, {Tai Ho} and Kim, {You Ho} and Sung, {Jung Hoon} and Lee, {Young Soo} and Cho, {Jeong Gwan} and Oh, {Dong Jin} and Kim, {Dae Kyeong} and June Namgung and Park, {Kyoung Min} and Kim, {Yong Hoon} and Kim, {Yoon Nyun} and Lim, {Hong Euy} and Cha, {Tae Joon} and On, {Young Keun} and Shin, {Dong Gu} and Pak, {Hui Nam} and Kim, {Nam Ho}",
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Uhm, JS, Hwang, IU, Oh, YS, Choi, MS, Jang, SW, Shin, WS, Kim, JH, Lee, MY, Rho, TH, Kim, YH, Sung, JH, Lee, YS, Cho, JG, Oh, DJ, Kim, DK, Namgung, J, Park, KM, Kim, YH, Kim, YN, Lim, HE, Cha, TJ, On, YK, Shin, DG, Pak, HN & Kim, NH 2011, 'Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men', PACE - Pacing and Clinical Electrophysiology, vol. 34, no. 6, pp. 717-723. https://doi.org/10.1111/j.1540-8159.2010.03024.x

Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men. / Uhm, Jae Sun; Hwang, Il Ung; Oh, Yong Seog; Choi, Min Seok; Jang, Sung Won; Shin, Woo Seung; Kim, Ji Hoon; Lee, Man Young; Rho, Tai Ho; Kim, You Ho; Sung, Jung Hoon; Lee, Young Soo; Cho, Jeong Gwan; Oh, Dong Jin; Kim, Dae Kyeong; Namgung, June; Park, Kyoung Min; Kim, Yong Hoon; Kim, Yoon Nyun; Lim, Hong Euy; Cha, Tae Joon; On, Young Keun; Shin, Dong Gu; Pak, Hui Nam; Kim, Nam Ho.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 34, No. 6, 01.06.2011, p. 717-723.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Prevalence of electrocardiographic findings suggestive of sudden cardiac death risk in 10,867 apparently healthy young Korean men

AU - Uhm, Jae Sun

AU - Hwang, Il Ung

AU - Oh, Yong Seog

AU - Choi, Min Seok

AU - Jang, Sung Won

AU - Shin, Woo Seung

AU - Kim, Ji Hoon

AU - Lee, Man Young

AU - Rho, Tai Ho

AU - Kim, You Ho

AU - Sung, Jung Hoon

AU - Lee, Young Soo

AU - Cho, Jeong Gwan

AU - Oh, Dong Jin

AU - Kim, Dae Kyeong

AU - Namgung, June

AU - Park, Kyoung Min

AU - Kim, Yong Hoon

AU - Kim, Yoon Nyun

AU - Lim, Hong Euy

AU - Cha, Tae Joon

AU - On, Young Keun

AU - Shin, Dong Gu

AU - Pak, Hui Nam

AU - Kim, Nam Ho

PY - 2011/6/1

Y1 - 2011/6/1

N2 - Background: The objective of this study was to determine the prevalence of electrocardiographic (ECG) findings suggestive of sudden cardiac death risk in apparently healthy young Korean men. Methods: We administered questionnaires that elicited personal and family histories and performed ECGs on 10,867 male subjects (mean age, 20.9 years). The subjects with abnormal ECG findings underwent echocardiography, a treadmill test, Holter monitoring, a flecainide provocation test, or an electrophysiologic study (EPS) according to the ECG findings and histories. Results: Of the subjects, 5.95% had left ventricular hypertrophy on ECG, but no subjects had hypertrophic cardiomyopathy by echocardiography. The percentage of subjects with a Brugada ECG pattern was 0.90%. We identified one subject with a positive result on the flecainide provocation test. The percentage of subjects with a preexcitation ECG was 0.17%. In two of the subjects, supraventricular tachycardia was induced in the EPS. Of the subjects, 0.05% had epsilon waves, but there were no subjects with arrhythmogenic right ventricular dysplasia/cardiomyopathy by echocardiography. The percentage of subjects with long QT intervals was 0.02%, but there were no arrhythmias on the treadmill test or Holter monitoring. Conclusions: The prevalence of a Brugada ECG pattern in apparently healthy young men is higher in Korea than other countries.

AB - Background: The objective of this study was to determine the prevalence of electrocardiographic (ECG) findings suggestive of sudden cardiac death risk in apparently healthy young Korean men. Methods: We administered questionnaires that elicited personal and family histories and performed ECGs on 10,867 male subjects (mean age, 20.9 years). The subjects with abnormal ECG findings underwent echocardiography, a treadmill test, Holter monitoring, a flecainide provocation test, or an electrophysiologic study (EPS) according to the ECG findings and histories. Results: Of the subjects, 5.95% had left ventricular hypertrophy on ECG, but no subjects had hypertrophic cardiomyopathy by echocardiography. The percentage of subjects with a Brugada ECG pattern was 0.90%. We identified one subject with a positive result on the flecainide provocation test. The percentage of subjects with a preexcitation ECG was 0.17%. In two of the subjects, supraventricular tachycardia was induced in the EPS. Of the subjects, 0.05% had epsilon waves, but there were no subjects with arrhythmogenic right ventricular dysplasia/cardiomyopathy by echocardiography. The percentage of subjects with long QT intervals was 0.02%, but there were no arrhythmias on the treadmill test or Holter monitoring. Conclusions: The prevalence of a Brugada ECG pattern in apparently healthy young men is higher in Korea than other countries.

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