Prevalence of gastrointestinal and cardiovascular risk in patients with degenerative lumbar spinal disease

Jae Ho Yang, Byoung Ho Lee, Kwang Sik Eum, Kyoung Soo Suk, Jin Oh Park, Hak Sun Kim, Hwan Mo Lee, Seong Hwan Moon

Research output: Contribution to journalArticle

Abstract

Background: Limited information is available about the proportion of patients with degenerative lumbar spinal disease (DLSD) who have gastrointestinal (GI) and cardiovascular (CV) risk factors. Many DLSD patients are prescribed nonsteroidal anti-inflamma-tory drugs (NSAIDs) that are known to carry risks to the GI and CV systems by increasing GI bleeding and thromboembolic events. This study aimed to measure the prevalence of GI and CV risk in patients with DLSD and to ascertain whether the prescription of NSAIDs is in line with current guidelines. Methods: This study included 153 patients with symptomatic DLSD who were planning to undergo lumbar spinal surgery. The GI profile was checked using the GI Standardized Calculator of Risk for Event system and CV risk was evaluated using the presence of metabolic syndrome. The conformity of the prescription of NSAIDs was investigated according to the recommendations in current guidelines. Results: More than half of the patients (59.5%) had high or very high GI risk, and 66% of the patients were diagnosed with metabolic syndrome, which corresponds with CV risk. The rate of simultaneous GI and CV risk was 40.5% (n = 62 / 153; gastrointestinal Standardized Calculator of Risk for Event, > high and metabolic syndrome, yes). The actual prescription of NSAIDs was not in ac-cordance with current guidelines. Conclusions: Two out of 3 patients had GI or CV risk factors, and approximately 40% of patients had both. Detailed assessment of GI and CV risk in patients with DLSD by using effective evaluation tools is mandatory for optimal medical treatment.

Original languageEnglish
Pages (from-to)343-352
Number of pages10
JournalCiOS Clinics in Orthopedic Surgery
Volume12
Issue number3
DOIs
Publication statusPublished - 2020 Sep

All Science Journal Classification (ASJC) codes

  • Surgery
  • Orthopedics and Sports Medicine

Fingerprint Dive into the research topics of 'Prevalence of gastrointestinal and cardiovascular risk in patients with degenerative lumbar spinal disease'. Together they form a unique fingerprint.

  • Cite this