Prevalence of intracranial aneurysms in patients with aortic dissection

W. S. Jung, J. H. Kim, S. J. Ahn, S. W. Song, Byungmoon Kim, K. D. Seo, S. H. Suh

Research output: Contribution to journalArticle

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Abstract

BACKGROUND AND PURPOSE: There is an uncertainty about the association between intracranial aneurysms and aortic dissection. We aimed to determine the prevalence of intracranial aneurysms in patients with aortic dissection and evaluate the independent risk factors for the presence of intracranial aneurysms in these patients. MATERIALS AND METHODS: Seventy-one patients with a confirmed aortic dissection who underwent additional brain imaging were enrolled as the aortic dissection group, and 2118 healthy individuals with brain imaging, as controls. Demographic data were obtained from their medical records, including age, sex, comorbidities, and arch vessel involvement of aortic dissection. Two readers reviewed all brain images independently regarding the presence, morphology, size, and location of intracranial aneurysms. Baseline characteristics were compared between the aortic dissection group and controls by propensity score matching, and logistic regression analysis was performed for independent risk factors for the presence of intracranial aneurysms. RESULTS: The prevalence of intracranial aneurysms was 12.96% in the aortic dissection group and 1.85% in controls (P = .022). The mean diameter of intracranial aneurysms was significantly larger in the aortic dissection group (5.79±3.26mmin aortic dissection versus 3.04± 1.57 mm in controls; P = .008), and intracranial aneurysms of >7 mm were also more common in the aortic dissection group (28.6% in aortic dissection versus 5.3% in controls, P=.003). On multivariate analysis, arch vessel involvement of aortic dissection was an independent risk factor for the presence of intracranial aneurysms (odds ratio, 6.246; 95% confidence interval, 1.472-26.50; P=.013). CONCLUSIONS: Patients with aortic dissection have a high prevalence of intracranial aneurysms, and selective screening for brain vessels could be considered in these patients with arch vessel involvement. A further prospective study is needed to demonstrate a substantial prevalence of intracranial aneurysms.

Original languageEnglish
Pages (from-to)2089-2093
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume38
Issue number11
DOIs
Publication statusPublished - 2017 Nov 1

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Intracranial Aneurysm
Dissection
Neuroimaging
Propensity Score
Brain
Uncertainty
Medical Records
Comorbidity
Multivariate Analysis
Logistic Models
Odds Ratio
Regression Analysis
Demography
Prospective Studies

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Jung, W. S., Kim, J. H., Ahn, S. J., Song, S. W., Kim, B., Seo, K. D., & Suh, S. H. (2017). Prevalence of intracranial aneurysms in patients with aortic dissection. American Journal of Neuroradiology, 38(11), 2089-2093. https://doi.org/10.3174/ajnr.A5359
Jung, W. S. ; Kim, J. H. ; Ahn, S. J. ; Song, S. W. ; Kim, Byungmoon ; Seo, K. D. ; Suh, S. H. / Prevalence of intracranial aneurysms in patients with aortic dissection. In: American Journal of Neuroradiology. 2017 ; Vol. 38, No. 11. pp. 2089-2093.
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Jung, WS, Kim, JH, Ahn, SJ, Song, SW, Kim, B, Seo, KD & Suh, SH 2017, 'Prevalence of intracranial aneurysms in patients with aortic dissection', American Journal of Neuroradiology, vol. 38, no. 11, pp. 2089-2093. https://doi.org/10.3174/ajnr.A5359

Prevalence of intracranial aneurysms in patients with aortic dissection. / Jung, W. S.; Kim, J. H.; Ahn, S. J.; Song, S. W.; Kim, Byungmoon; Seo, K. D.; Suh, S. H.

In: American Journal of Neuroradiology, Vol. 38, No. 11, 01.11.2017, p. 2089-2093.

Research output: Contribution to journalArticle

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