Prevalence of self-reported allergic diseases and IgE levels

A 2010 KNHANES analysis

Hye Jung Park, Eun Jin Kim, Dankyu Yoon, Jeom Kyu Lee, Woo Sung Chang, Yoen Mi Lim, Jungwon Park, Joo Shil Lee

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Purpose: The prevalence of allergic diseases is known to be associated with both demographic and environmental factors. Herein, we aimed to determine significant factors associated with the prevalence of allergic diseases and with total immunoglobulin E (tIgE) and specific immunoglobulin E (sIgE) levels in Korea. Methods: We analyzed unweighted data collected by the 2010 Korea National Health and Nutrition Examination Survey for 2,342 subjects who underwent serum tests for tIgE and sIgE to Dermatophagoides farinae, dog, and Blattella germanica, representing a sample of 16,003,645 citizens, by considering the sample weight and stratification. Results: The overall prevalence of self-reported allergic diseases was 37.6%. The prevalence rates of allergic rhinitis and atopic dermatitis decreased with age, whereas the asthma prevalence was not affected by the age of the subjects. When analyzed according to the type of allergic diseases, the prevalence of self-reported allergic disease was significantly associated with various factors (e.g. age, occupation, living in urban areas, and depression). The tIgE level decreased with age, but later increased. Elevation of tIgE was significantly associated with male sex, type of occupation, obesity, and smoking status. However, the risk factors for the increased sIgE levels to each allergen were quite different. Sensitization to D. farinae was more likely in young subjects, whereas the prevalence of sensitization to B. germanica was significantly higher in subjects with male sex, residing in a house (houses), and with glucose intolerance. Finally, young age and the smoking status were significantly associated with sensitization to dog. Conclusions: Various demographic and environmental factors were significantly associated with the prevalence of self-reported allergic diseases and the levels of tIgE and sIgE to D. farinae, B. germanica, and dog in Korea.

Original languageEnglish
Pages (from-to)329-339
Number of pages11
JournalAllergy, Asthma and Immunology Research
Volume9
Issue number4
DOIs
Publication statusPublished - 2017 Jan 1

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Immunoglobulin E
Dermatophagoides farinae
Korea
Dogs
Occupations
Smoking
Demography
Glucose Intolerance
Nutrition Surveys
Age Factors
Atopic Dermatitis
Allergens
Asthma
Obesity
Depression
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine

Cite this

Park, H. J., Kim, E. J., Yoon, D., Lee, J. K., Chang, W. S., Lim, Y. M., ... Lee, J. S. (2017). Prevalence of self-reported allergic diseases and IgE levels: A 2010 KNHANES analysis. Allergy, Asthma and Immunology Research, 9(4), 329-339. https://doi.org/10.4168/aair.2017.9.4.329
Park, Hye Jung ; Kim, Eun Jin ; Yoon, Dankyu ; Lee, Jeom Kyu ; Chang, Woo Sung ; Lim, Yoen Mi ; Park, Jungwon ; Lee, Joo Shil. / Prevalence of self-reported allergic diseases and IgE levels : A 2010 KNHANES analysis. In: Allergy, Asthma and Immunology Research. 2017 ; Vol. 9, No. 4. pp. 329-339.
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Prevalence of self-reported allergic diseases and IgE levels : A 2010 KNHANES analysis. / Park, Hye Jung; Kim, Eun Jin; Yoon, Dankyu; Lee, Jeom Kyu; Chang, Woo Sung; Lim, Yoen Mi; Park, Jungwon; Lee, Joo Shil.

In: Allergy, Asthma and Immunology Research, Vol. 9, No. 4, 01.01.2017, p. 329-339.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Prevalence of self-reported allergic diseases and IgE levels

T2 - A 2010 KNHANES analysis

AU - Park, Hye Jung

AU - Kim, Eun Jin

AU - Yoon, Dankyu

AU - Lee, Jeom Kyu

AU - Chang, Woo Sung

AU - Lim, Yoen Mi

AU - Park, Jungwon

AU - Lee, Joo Shil

PY - 2017/1/1

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N2 - Purpose: The prevalence of allergic diseases is known to be associated with both demographic and environmental factors. Herein, we aimed to determine significant factors associated with the prevalence of allergic diseases and with total immunoglobulin E (tIgE) and specific immunoglobulin E (sIgE) levels in Korea. Methods: We analyzed unweighted data collected by the 2010 Korea National Health and Nutrition Examination Survey for 2,342 subjects who underwent serum tests for tIgE and sIgE to Dermatophagoides farinae, dog, and Blattella germanica, representing a sample of 16,003,645 citizens, by considering the sample weight and stratification. Results: The overall prevalence of self-reported allergic diseases was 37.6%. The prevalence rates of allergic rhinitis and atopic dermatitis decreased with age, whereas the asthma prevalence was not affected by the age of the subjects. When analyzed according to the type of allergic diseases, the prevalence of self-reported allergic disease was significantly associated with various factors (e.g. age, occupation, living in urban areas, and depression). The tIgE level decreased with age, but later increased. Elevation of tIgE was significantly associated with male sex, type of occupation, obesity, and smoking status. However, the risk factors for the increased sIgE levels to each allergen were quite different. Sensitization to D. farinae was more likely in young subjects, whereas the prevalence of sensitization to B. germanica was significantly higher in subjects with male sex, residing in a house (houses), and with glucose intolerance. Finally, young age and the smoking status were significantly associated with sensitization to dog. Conclusions: Various demographic and environmental factors were significantly associated with the prevalence of self-reported allergic diseases and the levels of tIgE and sIgE to D. farinae, B. germanica, and dog in Korea.

AB - Purpose: The prevalence of allergic diseases is known to be associated with both demographic and environmental factors. Herein, we aimed to determine significant factors associated with the prevalence of allergic diseases and with total immunoglobulin E (tIgE) and specific immunoglobulin E (sIgE) levels in Korea. Methods: We analyzed unweighted data collected by the 2010 Korea National Health and Nutrition Examination Survey for 2,342 subjects who underwent serum tests for tIgE and sIgE to Dermatophagoides farinae, dog, and Blattella germanica, representing a sample of 16,003,645 citizens, by considering the sample weight and stratification. Results: The overall prevalence of self-reported allergic diseases was 37.6%. The prevalence rates of allergic rhinitis and atopic dermatitis decreased with age, whereas the asthma prevalence was not affected by the age of the subjects. When analyzed according to the type of allergic diseases, the prevalence of self-reported allergic disease was significantly associated with various factors (e.g. age, occupation, living in urban areas, and depression). The tIgE level decreased with age, but later increased. Elevation of tIgE was significantly associated with male sex, type of occupation, obesity, and smoking status. However, the risk factors for the increased sIgE levels to each allergen were quite different. Sensitization to D. farinae was more likely in young subjects, whereas the prevalence of sensitization to B. germanica was significantly higher in subjects with male sex, residing in a house (houses), and with glucose intolerance. Finally, young age and the smoking status were significantly associated with sensitization to dog. Conclusions: Various demographic and environmental factors were significantly associated with the prevalence of self-reported allergic diseases and the levels of tIgE and sIgE to D. farinae, B. germanica, and dog in Korea.

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