Primary lymphoma of bone--survival and prognosis.

Jun Yong Choi, Jee Sook Hahn, Chang Ok Suh, Woo Ick Yang

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND: Primary lymphoma of bone is a rare disease. There is yet no systematical evaluation of primary lymphoma of bone in Korea. Here we report our experience of sixteen cases with primary lymphoma of bone focusing on the survival. METHODS: Sixteen cases, collected for 13 years, were evaluated on the clinical presentation, histologic subtype, stage and treatment outcomes of the primary bone lymphoma. RESULTS: The most common presenting complaint was bone pain. Malignant lymphoma of bone involved a wide variety of sites, the most prevalent site of which in this study was the spine. Most of the cases were in the diffuse large B-cell category. The clinical stage of lymphoma was IEA in two cases, IIEA in three cases, IVEA in five cases and IVEB in three cases. All treated cases received systemic chemotherapy and ten cases among them were treated with combined modality therapy. Median overall survival was not reached after median follow-up period of 28 months and five-year overall survival rate was 54%. CONCLUSION: More promising therapeutic strategies are needed for survival improvement on more accumulated cases.

Original languageEnglish
Pages (from-to)191-197
Number of pages7
JournalThe Korean journal of internal medicine
Volume17
Issue number3
Publication statusPublished - 2002 Sep

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Lymphoma
Bone and Bones
Combined Modality Therapy
Korea
Rare Diseases
Spine
B-Lymphocytes
Drug Therapy
Pain
Therapeutics

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Choi, Jun Yong ; Hahn, Jee Sook ; Suh, Chang Ok ; Yang, Woo Ick. / Primary lymphoma of bone--survival and prognosis. In: The Korean journal of internal medicine. 2002 ; Vol. 17, No. 3. pp. 191-197.
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Primary lymphoma of bone--survival and prognosis. / Choi, Jun Yong; Hahn, Jee Sook; Suh, Chang Ok; Yang, Woo Ick.

In: The Korean journal of internal medicine, Vol. 17, No. 3, 09.2002, p. 191-197.

Research output: Contribution to journalArticle

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AB - BACKGROUND: Primary lymphoma of bone is a rare disease. There is yet no systematical evaluation of primary lymphoma of bone in Korea. Here we report our experience of sixteen cases with primary lymphoma of bone focusing on the survival. METHODS: Sixteen cases, collected for 13 years, were evaluated on the clinical presentation, histologic subtype, stage and treatment outcomes of the primary bone lymphoma. RESULTS: The most common presenting complaint was bone pain. Malignant lymphoma of bone involved a wide variety of sites, the most prevalent site of which in this study was the spine. Most of the cases were in the diffuse large B-cell category. The clinical stage of lymphoma was IEA in two cases, IIEA in three cases, IVEA in five cases and IVEB in three cases. All treated cases received systemic chemotherapy and ten cases among them were treated with combined modality therapy. Median overall survival was not reached after median follow-up period of 28 months and five-year overall survival rate was 54%. CONCLUSION: More promising therapeutic strategies are needed for survival improvement on more accumulated cases.

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