Probabilistic approach for sensing performances of localized surface plasmon resonance biosensors

Heejin Yang, Wonju Lee, Taewon Hwang, Donghyun Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We analyze sensing performances of localized surface plasmon resonance biosensors based on the overlap between target distribution and local field intensity produced by silver nanoislands in three detection models of non-specific, non-colocalized, and colocalized detection. The behavior of biomolecules was modeled to follow a probabilistic model using Poisson distribution. The results have found that the colocalized detection achieves the highest overlap signature with the smallest uncertainty and can enhance the limit of detection by more than 10000 times compared to conventional non-specific detection.

Original languageEnglish
Title of host publicationInternational Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015, NBSIS 2015
EditorsDonghyun Kim, Min-Gon Kim, Seung-Han Park
PublisherSPIE
ISBN (Electronic)9781628416794
DOIs
Publication statusPublished - 2015 Jan 1
Event2nd International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy, NBSIS 2015 - Jeju, Korea, Republic of
Duration: 2015 Feb 252015 Feb 27

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9523
ISSN (Print)1605-7422

Other

Other2nd International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy, NBSIS 2015
CountryKorea, Republic of
CityJeju
Period15/2/2515/2/27

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Yang, H., Lee, W., Hwang, T., & Kim, D. (2015). Probabilistic approach for sensing performances of localized surface plasmon resonance biosensors. In D. Kim, M-G. Kim, & S-H. Park (Eds.), International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015, NBSIS 2015 [95230L] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9523). SPIE. https://doi.org/10.1117/12.2189429