TY - JOUR
T1 - Production of uniform emulsion droplets using a simple fluidic device with a peristaltic pump
AU - Hwang, Seok Joon
AU - Moon, Seung Kwan
AU - Kim, Sung Eun
AU - Kim, Jung Hyun
AU - Choi, Sung Wook
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/5
Y1 - 2014/5
N2 - We fabricated a simple fluidic device consisting of a needle, a glass capillary, and a Tygon® tube to produce oil-in-water (O/W) emulsion droplets. In the fluidic device, the flow rate of the continuous phase was adjusted by a syringe or peristaltic pump, where a syringe pump was used for the discontinuous phase. We compared the performance of the syringe and peristaltic pump for the continuous phase in terms of the average diameter and coefficient of variance of the resultant O/W emulsion droplets. It was found that uniform droplets could be obtained when the production frequency was well matched. In addition, the flow behavior of the discontinuous phase during droplet formation was monitored using a high-speed camera, observing the back pressure in the peristaltic pump. By employment of a peristaltic pump for the continuous phase, it was possible to prepare a large amount of emulsion droplets.
AB - We fabricated a simple fluidic device consisting of a needle, a glass capillary, and a Tygon® tube to produce oil-in-water (O/W) emulsion droplets. In the fluidic device, the flow rate of the continuous phase was adjusted by a syringe or peristaltic pump, where a syringe pump was used for the discontinuous phase. We compared the performance of the syringe and peristaltic pump for the continuous phase in terms of the average diameter and coefficient of variance of the resultant O/W emulsion droplets. It was found that uniform droplets could be obtained when the production frequency was well matched. In addition, the flow behavior of the discontinuous phase during droplet formation was monitored using a high-speed camera, observing the back pressure in the peristaltic pump. By employment of a peristaltic pump for the continuous phase, it was possible to prepare a large amount of emulsion droplets.
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U2 - 10.1007/s13233-014-2074-1
DO - 10.1007/s13233-014-2074-1
M3 - Article
AN - SCOPUS:84901835700
VL - 22
SP - 557
EP - 561
JO - Macromolecular Research
JF - Macromolecular Research
SN - 1598-5032
IS - 5
ER -