Profiling of glycosidase activities using coumarin-conjugated glycoside cocktails

Sungjin Park, Injae Shin

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Glycosidases are a large subgroup of carbohydrate-processing enzymes that hydrolytically cleave the glycosidic bond. Glycans formed by the action of glycosidases are involved in various biological processes. Genetic abnormalities in glycosidases are associated with inherited diseases. Thus, characterization of the catalytic activities of glycosidases is of great importance. Herein, we describe a simple and rapid approach for determining glycosidase activity profiles using coumarin-conjugated glycoside cocktails.

Original languageEnglish
Pages (from-to)619-622
Number of pages4
JournalOrganic Letters
Volume9
Issue number4
DOIs
Publication statusPublished - 2007 Feb 15

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glucosides
Glycoside Hydrolases
carbohydrates
abnormalities
Glycosides
subgroups
catalytic activity
enzymes
profiles
Biological Phenomena
Polysaccharides
Catalyst activity
Carbohydrates
coumarin
Enzymes
Processing

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

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abstract = "Glycosidases are a large subgroup of carbohydrate-processing enzymes that hydrolytically cleave the glycosidic bond. Glycans formed by the action of glycosidases are involved in various biological processes. Genetic abnormalities in glycosidases are associated with inherited diseases. Thus, characterization of the catalytic activities of glycosidases is of great importance. Herein, we describe a simple and rapid approach for determining glycosidase activity profiles using coumarin-conjugated glycoside cocktails.",
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Profiling of glycosidase activities using coumarin-conjugated glycoside cocktails. / Park, Sungjin; Shin, Injae.

In: Organic Letters, Vol. 9, No. 4, 15.02.2007, p. 619-622.

Research output: Contribution to journalArticle

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AU - Shin, Injae

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