Prognostic role of carotid intima-media thickness in off-pump coronary artery bypass surgery

Sung Yeon Ham, Jong Wook Song, Jae Kwang Shim, Sarah Soh, Hee Jung Kim, Young Lan Kwak

Research output: Contribution to journalArticle

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Abstract

Carotid intima-media thickness (IMT) is a well-known predictor of adverse outcomes in the ischemic heart disease patients; however, evidence is lacking in patients undergoing off-pump coronary artery bypass surgery (OPCAB). Data from 407 patients who underwent OPCAB between April 2013 and August 2016 were retrospectively reviewed. A composite of cardiovascular morbidity endpoints was defined as the presence of stroke, acute myocardial infarction, new cardiac arrhythmia (newly developed atrial fibrillation, atrial flutter, or atrioventricular block), cardiovascular death, or cerebrovascular death within 30 days after surgery. Increased carotid IMT was defined as ≥0.9 mm on one or both sides. The incidence of a composite of cardiovascular morbidity endpoints was 24.0% in the normal IMT group (n = 221) and 34.4% in the increased IMT group (n = 186) (p = 0.021). Multivariable analysis revealed increased IMT (odds ratio 1.719, 95% confidence interval 1.108 to 2.666, p = 0.016) and preoperative renal replacement therapy (odds ratio 4.264, 95% confidence interval 1.679 to 10.829, p = 0.002) as independent predictors of a composite of cardiovascular morbidity endpoints. In patients undergoing OPCAB, preoperative assessment of carotid IMT may help predicting the development of a postoperative composite of cardiovascular morbidity endpoints.

Original languageEnglish
Article number11385
JournalScientific reports
Volume8
Issue number1
DOIs
Publication statusPublished - 2018 Dec 1

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Off-Pump Coronary Artery Bypass
Carotid Intima-Media Thickness
Coronary Artery Bypass
Morbidity
Odds Ratio
Confidence Intervals
Atrial Flutter
Renal Replacement Therapy
Atrioventricular Block
Ambulatory Surgical Procedures
Atrial Fibrillation
Myocardial Ischemia
Cardiac Arrhythmias
Stroke
Myocardial Infarction
Incidence

All Science Journal Classification (ASJC) codes

  • General

Cite this

Ham, Sung Yeon ; Song, Jong Wook ; Shim, Jae Kwang ; Soh, Sarah ; Kim, Hee Jung ; Kwak, Young Lan. / Prognostic role of carotid intima-media thickness in off-pump coronary artery bypass surgery. In: Scientific reports. 2018 ; Vol. 8, No. 1.
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abstract = "Carotid intima-media thickness (IMT) is a well-known predictor of adverse outcomes in the ischemic heart disease patients; however, evidence is lacking in patients undergoing off-pump coronary artery bypass surgery (OPCAB). Data from 407 patients who underwent OPCAB between April 2013 and August 2016 were retrospectively reviewed. A composite of cardiovascular morbidity endpoints was defined as the presence of stroke, acute myocardial infarction, new cardiac arrhythmia (newly developed atrial fibrillation, atrial flutter, or atrioventricular block), cardiovascular death, or cerebrovascular death within 30 days after surgery. Increased carotid IMT was defined as ≥0.9 mm on one or both sides. The incidence of a composite of cardiovascular morbidity endpoints was 24.0{\%} in the normal IMT group (n = 221) and 34.4{\%} in the increased IMT group (n = 186) (p = 0.021). Multivariable analysis revealed increased IMT (odds ratio 1.719, 95{\%} confidence interval 1.108 to 2.666, p = 0.016) and preoperative renal replacement therapy (odds ratio 4.264, 95{\%} confidence interval 1.679 to 10.829, p = 0.002) as independent predictors of a composite of cardiovascular morbidity endpoints. In patients undergoing OPCAB, preoperative assessment of carotid IMT may help predicting the development of a postoperative composite of cardiovascular morbidity endpoints.",
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Prognostic role of carotid intima-media thickness in off-pump coronary artery bypass surgery. / Ham, Sung Yeon; Song, Jong Wook; Shim, Jae Kwang; Soh, Sarah; Kim, Hee Jung; Kwak, Young Lan.

In: Scientific reports, Vol. 8, No. 1, 11385, 01.12.2018.

Research output: Contribution to journalArticle

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