Abstract
Objectives/Hypothesis: In this study, we retrospectively reviewed medical records of patients who underwent surgery for p16+ oropharyngeal cancer and analyzed the prognostic implications of pathologic lymph node (LN) status, including number of metastatic LNs, LN ratio, and location of metastatic LNs. Study Design: Retrospective case series. Methods: We retrospectively reviewed data on patients diagnosed with p16+ oropharyngeal cancer. Results: The study population consisted of 159 males and 29 females with a mean age of 57.2 years. The primary tumor sites were tonsils (n = 160), base of the tongue (n = 24), and soft palate (n = 4). Only recurrence-free survival (RFS) showed a significant correlation with contralateral LN metastasis on multivariate analysis. On Kaplan-Meier analysis, 5-year RFS was 92.4% in patients without contralateral LN metastasis and 68.8% in patients with contralateral LN metastasis. Conclusions: Among pathologic LN status in p16+ oropharyngeal cancer, only contralateral LN metastasis showed prognostic significance in disease recurrence of p16+ oropharyngeal squamous cell carcinoma patients. Level of Evidence: 4 Laryngoscope, 130: 1973–1979, 2020.
| Original language | English |
|---|---|
| Pages (from-to) | 1973-1979 |
| Number of pages | 7 |
| Journal | Laryngoscope |
| Volume | 130 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2020 Aug 1 |
Bibliographical note
Publisher Copyright:© 2020 The American Laryngological, Rhinological and Otological Society, Inc.
All Science Journal Classification (ASJC) codes
- Otorhinolaryngology
