Projection of breast cancer burden due to reproductive/lifestyle changes in Korean Women (2013-2030) using an age-period-cohort model

Joo Eun Lee, Sang Ah Lee, Tae Hyun Kim, Sohee Park, Yoon Soo Choy, Yeong Jun Ju, Eun Cheol Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose The aim of this study was to estimate the burden of breast cancer that can be attributed to rapid lifestyle changes in South Korea in 2013-2030. Materials and Methods An age-period-cohort model was used to estimate the incidence and mortality. The Global Burden of Disease Study Group method was used to calculate the years of life lost and years lived with disability in breast cancer patients using a nationwide cancer registry. The population attributable risks were calculated using meta-analyzed relative risk ratios and by assessing the prevalence of risk factors. Results Women's reproductive/lifestyle changes, including advanced maternal age at first childbirth (from 37 to 85 disability-adjusted life years [DALYs] per 100,000 person-years), total period of breastfeeding (from 22 to 46 DALYs per 100,000 person-years), obesity (from 37 to 61 DALYs per 100,000 person-years), alcohol consumption (from 19 to 39 DALYs per 100,000 person-years), oral contraceptive use (from 18 to 27 DALYs per 100,000 person-years), and hormone replacement therapy use (from 2 to 3 DALYs per 100,000 person-years) were identified as factors likely to increase the burden of breast cancer from 2013 to 2030. Approximately, 34.2% to 44.3% of the burden of breast cancer could be avoidable in 2030 with reduction in reproductive/lifestyle risk factors. Conclusion The rapid changes of age structure and lifestyle in South Korea during the last decade are expected to strongly increase the breast cancer burden over time unless the risk factors can be effectively modified.

Original languageEnglish
Pages (from-to)1388-1395
Number of pages8
JournalCancer Research and Treatment
Volume50
Issue number4
DOIs
Publication statusPublished - 2018 Oct 1

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Quality-Adjusted Life Years
Life Style
Breast Neoplasms
Republic of Korea
Hormone Replacement Therapy
Maternal Age
Oral Contraceptives
Breast Feeding
Alcohol Drinking
Registries
Obesity
Odds Ratio
Parturition
Mortality
Incidence
Population
Neoplasms

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Lee, Joo Eun ; Lee, Sang Ah ; Kim, Tae Hyun ; Park, Sohee ; Choy, Yoon Soo ; Ju, Yeong Jun ; Park, Eun Cheol. / Projection of breast cancer burden due to reproductive/lifestyle changes in Korean Women (2013-2030) using an age-period-cohort model. In: Cancer Research and Treatment. 2018 ; Vol. 50, No. 4. pp. 1388-1395.
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title = "Projection of breast cancer burden due to reproductive/lifestyle changes in Korean Women (2013-2030) using an age-period-cohort model",
abstract = "Purpose The aim of this study was to estimate the burden of breast cancer that can be attributed to rapid lifestyle changes in South Korea in 2013-2030. Materials and Methods An age-period-cohort model was used to estimate the incidence and mortality. The Global Burden of Disease Study Group method was used to calculate the years of life lost and years lived with disability in breast cancer patients using a nationwide cancer registry. The population attributable risks were calculated using meta-analyzed relative risk ratios and by assessing the prevalence of risk factors. Results Women's reproductive/lifestyle changes, including advanced maternal age at first childbirth (from 37 to 85 disability-adjusted life years [DALYs] per 100,000 person-years), total period of breastfeeding (from 22 to 46 DALYs per 100,000 person-years), obesity (from 37 to 61 DALYs per 100,000 person-years), alcohol consumption (from 19 to 39 DALYs per 100,000 person-years), oral contraceptive use (from 18 to 27 DALYs per 100,000 person-years), and hormone replacement therapy use (from 2 to 3 DALYs per 100,000 person-years) were identified as factors likely to increase the burden of breast cancer from 2013 to 2030. Approximately, 34.2{\%} to 44.3{\%} of the burden of breast cancer could be avoidable in 2030 with reduction in reproductive/lifestyle risk factors. Conclusion The rapid changes of age structure and lifestyle in South Korea during the last decade are expected to strongly increase the breast cancer burden over time unless the risk factors can be effectively modified.",
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Projection of breast cancer burden due to reproductive/lifestyle changes in Korean Women (2013-2030) using an age-period-cohort model. / Lee, Joo Eun; Lee, Sang Ah; Kim, Tae Hyun; Park, Sohee; Choy, Yoon Soo; Ju, Yeong Jun; Park, Eun Cheol.

In: Cancer Research and Treatment, Vol. 50, No. 4, 01.10.2018, p. 1388-1395.

Research output: Contribution to journalArticle

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T1 - Projection of breast cancer burden due to reproductive/lifestyle changes in Korean Women (2013-2030) using an age-period-cohort model

AU - Lee, Joo Eun

AU - Lee, Sang Ah

AU - Kim, Tae Hyun

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AU - Choy, Yoon Soo

AU - Ju, Yeong Jun

AU - Park, Eun Cheol

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N2 - Purpose The aim of this study was to estimate the burden of breast cancer that can be attributed to rapid lifestyle changes in South Korea in 2013-2030. Materials and Methods An age-period-cohort model was used to estimate the incidence and mortality. The Global Burden of Disease Study Group method was used to calculate the years of life lost and years lived with disability in breast cancer patients using a nationwide cancer registry. The population attributable risks were calculated using meta-analyzed relative risk ratios and by assessing the prevalence of risk factors. Results Women's reproductive/lifestyle changes, including advanced maternal age at first childbirth (from 37 to 85 disability-adjusted life years [DALYs] per 100,000 person-years), total period of breastfeeding (from 22 to 46 DALYs per 100,000 person-years), obesity (from 37 to 61 DALYs per 100,000 person-years), alcohol consumption (from 19 to 39 DALYs per 100,000 person-years), oral contraceptive use (from 18 to 27 DALYs per 100,000 person-years), and hormone replacement therapy use (from 2 to 3 DALYs per 100,000 person-years) were identified as factors likely to increase the burden of breast cancer from 2013 to 2030. Approximately, 34.2% to 44.3% of the burden of breast cancer could be avoidable in 2030 with reduction in reproductive/lifestyle risk factors. Conclusion The rapid changes of age structure and lifestyle in South Korea during the last decade are expected to strongly increase the breast cancer burden over time unless the risk factors can be effectively modified.

AB - Purpose The aim of this study was to estimate the burden of breast cancer that can be attributed to rapid lifestyle changes in South Korea in 2013-2030. Materials and Methods An age-period-cohort model was used to estimate the incidence and mortality. The Global Burden of Disease Study Group method was used to calculate the years of life lost and years lived with disability in breast cancer patients using a nationwide cancer registry. The population attributable risks were calculated using meta-analyzed relative risk ratios and by assessing the prevalence of risk factors. Results Women's reproductive/lifestyle changes, including advanced maternal age at first childbirth (from 37 to 85 disability-adjusted life years [DALYs] per 100,000 person-years), total period of breastfeeding (from 22 to 46 DALYs per 100,000 person-years), obesity (from 37 to 61 DALYs per 100,000 person-years), alcohol consumption (from 19 to 39 DALYs per 100,000 person-years), oral contraceptive use (from 18 to 27 DALYs per 100,000 person-years), and hormone replacement therapy use (from 2 to 3 DALYs per 100,000 person-years) were identified as factors likely to increase the burden of breast cancer from 2013 to 2030. Approximately, 34.2% to 44.3% of the burden of breast cancer could be avoidable in 2030 with reduction in reproductive/lifestyle risk factors. Conclusion The rapid changes of age structure and lifestyle in South Korea during the last decade are expected to strongly increase the breast cancer burden over time unless the risk factors can be effectively modified.

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