Surface carbon contamination is a natural phenomenon. However, it interferes with cell-biomaterial interaction. In order to eliminate the interference, atmospheric pressure plasma treatment was employed. Dielectric barrier discharge treatment of titanium surface for less than 10 min turned titanium super-hydrophilic. Adsorption of fibronectin which is the major cell adhesive protein increased after plasma treatment. Cell attachment parameters of osteoblast cells such as population, cell area, perimeter, Feret's diameter and cytoskeleton development were also enhanced. Cell proliferation increased on the plasma treated titanium. In conclusion, dielectric barrier discharge type atmospheric pressure plasma system is effective to modify titanium surface and the modified titanium promotes cell and material interactions.
Bibliographical noteFunding Information:
This work was supported by National Research Foundation (NRF) of Korea Grant funded by the Korean Government (MEST) (grant number 2010-0002089 ) and was supported by a grant of the Korea Healthcare technology R&D Project, Ministry for Health & Welfare, Republic of Korea (grant number A100834 ). This article is dedicated to I. Han's lovely wife (Jeehae Choi) and pretty children (Jisu Han and Sangyoon Han).
All Science Journal Classification (ASJC) codes
- Condensed Matter Physics
- Physics and Astronomy(all)
- Surfaces and Interfaces
- Surfaces, Coatings and Films