TY - JOUR
T1 - Prostate cancer
T2 - Added value of subtraction dynamic imaging in 3T magnetic resonance imaging with a phased-array body coil
AU - Yu, Jeong Sik
AU - Chung, Jae Joon
AU - Hong, Soon Won
AU - Chung, Byung Ha
AU - Kim, Joo Hee
AU - Kim, Ki Whang
PY - 2008
Y1 - 2008
N2 - Purpose: To determine the added value of dynamic subtraction magnetic resonance (MR) imaging for the localization of prostate cancer. Materials and Methods: We examined 21 consecutive patients who underwent MR imaging in 3T unit with a phased-array body coil and then had radical prostatectomy. After T2-weighted fast spin-echo imaging, we performed a contrast-enhanced dynamic 3D gradient-echo imaging consisting of pre-contrast, 2 successive early-phased (first imaging was started just after the appearance of contrast material in the aortic bifurcation followed by second imaging 35 seconds after the initiation of first imaging) and one 5-minute delayed post-contrast series. Subtraction of precontrast images from corresponding post-contrast images of each phase was performed on the console. Results: On ROC analysis, the overall accuracy (Az value) of dynamic imaging combined with subtraction imaging was higher than T2-weighted imaging (p = 0.001) or conventional dynamic imaging alone (p = 0.074) for localization of cancer foci regardless of their zonal locations. Among pathologically verified 81 lesions, the mean volume of detected lesions with the subtraction images (n = 49, 0.69 cm3) was smaller than with T2-weighted images (n = 14, 1.05 cm3) or conventional dynamic images (n = 43, 0.71 cm3). Conclusion: For localization of small prostate cancer, additional subtraction for the dynamic imaging could be superior to both T2-weighted imaging and un-subtracted dynamic imaging.
AB - Purpose: To determine the added value of dynamic subtraction magnetic resonance (MR) imaging for the localization of prostate cancer. Materials and Methods: We examined 21 consecutive patients who underwent MR imaging in 3T unit with a phased-array body coil and then had radical prostatectomy. After T2-weighted fast spin-echo imaging, we performed a contrast-enhanced dynamic 3D gradient-echo imaging consisting of pre-contrast, 2 successive early-phased (first imaging was started just after the appearance of contrast material in the aortic bifurcation followed by second imaging 35 seconds after the initiation of first imaging) and one 5-minute delayed post-contrast series. Subtraction of precontrast images from corresponding post-contrast images of each phase was performed on the console. Results: On ROC analysis, the overall accuracy (Az value) of dynamic imaging combined with subtraction imaging was higher than T2-weighted imaging (p = 0.001) or conventional dynamic imaging alone (p = 0.074) for localization of cancer foci regardless of their zonal locations. Among pathologically verified 81 lesions, the mean volume of detected lesions with the subtraction images (n = 49, 0.69 cm3) was smaller than with T2-weighted images (n = 14, 1.05 cm3) or conventional dynamic images (n = 43, 0.71 cm3). Conclusion: For localization of small prostate cancer, additional subtraction for the dynamic imaging could be superior to both T2-weighted imaging and un-subtracted dynamic imaging.
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U2 - 10.3349/ymj.2008.49.5.765
DO - 10.3349/ymj.2008.49.5.765
M3 - Article
C2 - 18972597
AN - SCOPUS:58149478129
VL - 49
SP - 765
EP - 774
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 5
ER -