Punctate hyperfluorescent spots associated with polypoidal choroidal vasculopathy on indocyanine green angiography

Hyesun Kim, Ji Hwan Lee, Kye Yoon Kwon, Suk Ho Byeon, Sungchul Lee, Christopher Seungkyu Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: To evaluate punctate hyperfluorescent spots on indocyanine green angiography (ICGA) in eyes with polypoidal choroidal vasculopathy (PCV). PATIENTS AND METHODS: Retrospective observation case series of 88 eyes of 81 patients (63 men and 18 women) analyzing fundus photography, fluorescein angiography, ICGA, and spectral-domain optical coherence tomography (OCT) findings at baseline. RESULTS: Seven patients (9%) had bilateral PCV lesions. Mean age was 68.44 ± 5.94 years (range: 45 to 86 years). Macular-type PCV was found in 72 eyes (81.8%), peripapillary-type PCV in 12 eyes (13.6%), and combined-type PCV in four eyes (4.5%). Choroidal vascular hyperpermeability was observed in 38 eyes (43.2%), and punctate hyperfluorescent spots on ICGA in 47 eyes (53.4%). ICGA of unaffected fellow eyes of 74 patients with unilateral PCV revealed choroidal hyperpermeability in 23 eyes (31.1%) and punctate hyperfluorescent spots in 38 eyes (51.4%). Presence of punctate hyperfluorescent spots was significantly associated with choroidal vascular hyperpermeability (P < .001). CONCLUSION: Punctate hyperfluorescent spots were frequently observed in eyes with PCV in late-phase ICGA, as previously described in eyes with central serous chorioretinopathy, which may represent leakage from punctate hyperpermeable inner choroid spots or late staining of forme fruste drusen or drusen-like subretinal pigment epithelium deposits associated with choroidal hyperpermeability.

Original languageEnglish
Pages (from-to)423-427
Number of pages5
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume46
Issue number4
DOIs
Publication statusPublished - 2015 Apr 1

Fingerprint

Indocyanine Green
Angiography
Blood Vessels
Central Serous Chorioretinopathy
Choroid
Fluorescein Angiography
Photography
Optical Coherence Tomography
Epithelium
Observation

All Science Journal Classification (ASJC) codes

  • Surgery
  • Ophthalmology

Cite this

Kim, Hyesun ; Lee, Ji Hwan ; Kwon, Kye Yoon ; Byeon, Suk Ho ; Lee, Sungchul ; Lee, Christopher Seungkyu. / Punctate hyperfluorescent spots associated with polypoidal choroidal vasculopathy on indocyanine green angiography. In: Ophthalmic Surgery Lasers and Imaging Retina. 2015 ; Vol. 46, No. 4. pp. 423-427.
@article{2bb7a47b324644e8ae06b783d22fdbd5,
title = "Punctate hyperfluorescent spots associated with polypoidal choroidal vasculopathy on indocyanine green angiography",
abstract = "BACKGROUND AND OBJECTIVE: To evaluate punctate hyperfluorescent spots on indocyanine green angiography (ICGA) in eyes with polypoidal choroidal vasculopathy (PCV). PATIENTS AND METHODS: Retrospective observation case series of 88 eyes of 81 patients (63 men and 18 women) analyzing fundus photography, fluorescein angiography, ICGA, and spectral-domain optical coherence tomography (OCT) findings at baseline. RESULTS: Seven patients (9{\%}) had bilateral PCV lesions. Mean age was 68.44 ± 5.94 years (range: 45 to 86 years). Macular-type PCV was found in 72 eyes (81.8{\%}), peripapillary-type PCV in 12 eyes (13.6{\%}), and combined-type PCV in four eyes (4.5{\%}). Choroidal vascular hyperpermeability was observed in 38 eyes (43.2{\%}), and punctate hyperfluorescent spots on ICGA in 47 eyes (53.4{\%}). ICGA of unaffected fellow eyes of 74 patients with unilateral PCV revealed choroidal hyperpermeability in 23 eyes (31.1{\%}) and punctate hyperfluorescent spots in 38 eyes (51.4{\%}). Presence of punctate hyperfluorescent spots was significantly associated with choroidal vascular hyperpermeability (P < .001). CONCLUSION: Punctate hyperfluorescent spots were frequently observed in eyes with PCV in late-phase ICGA, as previously described in eyes with central serous chorioretinopathy, which may represent leakage from punctate hyperpermeable inner choroid spots or late staining of forme fruste drusen or drusen-like subretinal pigment epithelium deposits associated with choroidal hyperpermeability.",
author = "Hyesun Kim and Lee, {Ji Hwan} and Kwon, {Kye Yoon} and Byeon, {Suk Ho} and Sungchul Lee and Lee, {Christopher Seungkyu}",
year = "2015",
month = "4",
day = "1",
doi = "10.3928/23258160-20150422-04",
language = "English",
volume = "46",
pages = "423--427",
journal = "Ophthalmic Surgery Lasers and Imaging Retina",
issn = "2325-8160",
publisher = "Slack Incorporated",
number = "4",

}

Punctate hyperfluorescent spots associated with polypoidal choroidal vasculopathy on indocyanine green angiography. / Kim, Hyesun; Lee, Ji Hwan; Kwon, Kye Yoon; Byeon, Suk Ho; Lee, Sungchul; Lee, Christopher Seungkyu.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 46, No. 4, 01.04.2015, p. 423-427.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Punctate hyperfluorescent spots associated with polypoidal choroidal vasculopathy on indocyanine green angiography

AU - Kim, Hyesun

AU - Lee, Ji Hwan

AU - Kwon, Kye Yoon

AU - Byeon, Suk Ho

AU - Lee, Sungchul

AU - Lee, Christopher Seungkyu

PY - 2015/4/1

Y1 - 2015/4/1

N2 - BACKGROUND AND OBJECTIVE: To evaluate punctate hyperfluorescent spots on indocyanine green angiography (ICGA) in eyes with polypoidal choroidal vasculopathy (PCV). PATIENTS AND METHODS: Retrospective observation case series of 88 eyes of 81 patients (63 men and 18 women) analyzing fundus photography, fluorescein angiography, ICGA, and spectral-domain optical coherence tomography (OCT) findings at baseline. RESULTS: Seven patients (9%) had bilateral PCV lesions. Mean age was 68.44 ± 5.94 years (range: 45 to 86 years). Macular-type PCV was found in 72 eyes (81.8%), peripapillary-type PCV in 12 eyes (13.6%), and combined-type PCV in four eyes (4.5%). Choroidal vascular hyperpermeability was observed in 38 eyes (43.2%), and punctate hyperfluorescent spots on ICGA in 47 eyes (53.4%). ICGA of unaffected fellow eyes of 74 patients with unilateral PCV revealed choroidal hyperpermeability in 23 eyes (31.1%) and punctate hyperfluorescent spots in 38 eyes (51.4%). Presence of punctate hyperfluorescent spots was significantly associated with choroidal vascular hyperpermeability (P < .001). CONCLUSION: Punctate hyperfluorescent spots were frequently observed in eyes with PCV in late-phase ICGA, as previously described in eyes with central serous chorioretinopathy, which may represent leakage from punctate hyperpermeable inner choroid spots or late staining of forme fruste drusen or drusen-like subretinal pigment epithelium deposits associated with choroidal hyperpermeability.

AB - BACKGROUND AND OBJECTIVE: To evaluate punctate hyperfluorescent spots on indocyanine green angiography (ICGA) in eyes with polypoidal choroidal vasculopathy (PCV). PATIENTS AND METHODS: Retrospective observation case series of 88 eyes of 81 patients (63 men and 18 women) analyzing fundus photography, fluorescein angiography, ICGA, and spectral-domain optical coherence tomography (OCT) findings at baseline. RESULTS: Seven patients (9%) had bilateral PCV lesions. Mean age was 68.44 ± 5.94 years (range: 45 to 86 years). Macular-type PCV was found in 72 eyes (81.8%), peripapillary-type PCV in 12 eyes (13.6%), and combined-type PCV in four eyes (4.5%). Choroidal vascular hyperpermeability was observed in 38 eyes (43.2%), and punctate hyperfluorescent spots on ICGA in 47 eyes (53.4%). ICGA of unaffected fellow eyes of 74 patients with unilateral PCV revealed choroidal hyperpermeability in 23 eyes (31.1%) and punctate hyperfluorescent spots in 38 eyes (51.4%). Presence of punctate hyperfluorescent spots was significantly associated with choroidal vascular hyperpermeability (P < .001). CONCLUSION: Punctate hyperfluorescent spots were frequently observed in eyes with PCV in late-phase ICGA, as previously described in eyes with central serous chorioretinopathy, which may represent leakage from punctate hyperpermeable inner choroid spots or late staining of forme fruste drusen or drusen-like subretinal pigment epithelium deposits associated with choroidal hyperpermeability.

UR - http://www.scopus.com/inward/record.url?scp=84929405439&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929405439&partnerID=8YFLogxK

U2 - 10.3928/23258160-20150422-04

DO - 10.3928/23258160-20150422-04

M3 - Article

VL - 46

SP - 423

EP - 427

JO - Ophthalmic Surgery Lasers and Imaging Retina

JF - Ophthalmic Surgery Lasers and Imaging Retina

SN - 2325-8160

IS - 4

ER -