Qualitative analysis on crystal growth of synthetic hydroxyapatite influenced by fluoride concentration

Sumi Kang, Jeong Taeg Seo, Sungho Park, Il Young Jung, Chan Young Lee, Jeong Won Park

Research output: Contribution to journalArticle

Abstract

Objective: This study was designed to analyze the crystal growth of synthetic hydroxyapatite (HA) particles in pH 7.0 supersaturated solutions with different fluoride concentrations by FE-SEM, FE-TEM, X-ray diffraction (XRD), and FTIR. Design: Eight groups of pH 7.0 calcium phosphate supersaturated solutions were prepared with different fluoride concentrations (0, 1, 2, 4, 8, 16, 32, and 64 ppm). Each solution was introduced into the reactive column containing the synthetic HA for 48 h. The resulting products were prepared for FE-SEM, FE-TEM, XRD, and FTIR. Results: The FE-SEM examination revealed various morphological changes of the crystals, with additional, less-ordered crystallites in experimental solutions containing more than 8 ppm of fluoride. FE-TEM examination showed an additional amorphous layer on the surface of the crystals with the presence of fluoride, whereas definite lattice structures completely reached the surface of the crystals without fluorides. XRD data showed that all crystals had the same patterns as the unreacted synthetic HA, regardless of fluoride concentration. With FTIR results, the intensity of the OH-libration mode decreased when adding fluoride, compared to that of pristine HA. The resulting crystals were considered to be partially fluoridated HA under room temperature and pH 7.0 supersaturated solutions. Conclusion: Under the experimental conditions in this study, fluorides mainly react with the surface of the seed HA and have an impact on the growth of HA in a less effective manner as the concentration of fluoride increases.

Original languageEnglish
Pages (from-to)52-59
Number of pages8
JournalArchives of Oral Biology
Volume104
DOIs
Publication statusPublished - 2019 Aug 1

Fingerprint

Durapatite
Crystallization
Fluorides
Fourier Transform Infrared Spectroscopy
X-Ray Diffraction
Seeds
Temperature
Growth

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Dentistry(all)
  • Cell Biology

Cite this

Kang, Sumi ; Seo, Jeong Taeg ; Park, Sungho ; Jung, Il Young ; Lee, Chan Young ; Park, Jeong Won. / Qualitative analysis on crystal growth of synthetic hydroxyapatite influenced by fluoride concentration. In: Archives of Oral Biology. 2019 ; Vol. 104. pp. 52-59.
@article{a382fde8a5f4466aa16b6bf1c53286d9,
title = "Qualitative analysis on crystal growth of synthetic hydroxyapatite influenced by fluoride concentration",
abstract = "Objective: This study was designed to analyze the crystal growth of synthetic hydroxyapatite (HA) particles in pH 7.0 supersaturated solutions with different fluoride concentrations by FE-SEM, FE-TEM, X-ray diffraction (XRD), and FTIR. Design: Eight groups of pH 7.0 calcium phosphate supersaturated solutions were prepared with different fluoride concentrations (0, 1, 2, 4, 8, 16, 32, and 64 ppm). Each solution was introduced into the reactive column containing the synthetic HA for 48 h. The resulting products were prepared for FE-SEM, FE-TEM, XRD, and FTIR. Results: The FE-SEM examination revealed various morphological changes of the crystals, with additional, less-ordered crystallites in experimental solutions containing more than 8 ppm of fluoride. FE-TEM examination showed an additional amorphous layer on the surface of the crystals with the presence of fluoride, whereas definite lattice structures completely reached the surface of the crystals without fluorides. XRD data showed that all crystals had the same patterns as the unreacted synthetic HA, regardless of fluoride concentration. With FTIR results, the intensity of the OH-libration mode decreased when adding fluoride, compared to that of pristine HA. The resulting crystals were considered to be partially fluoridated HA under room temperature and pH 7.0 supersaturated solutions. Conclusion: Under the experimental conditions in this study, fluorides mainly react with the surface of the seed HA and have an impact on the growth of HA in a less effective manner as the concentration of fluoride increases.",
author = "Sumi Kang and Seo, {Jeong Taeg} and Sungho Park and Jung, {Il Young} and Lee, {Chan Young} and Park, {Jeong Won}",
year = "2019",
month = "8",
day = "1",
doi = "10.1016/j.archoralbio.2019.05.022",
language = "English",
volume = "104",
pages = "52--59",
journal = "Archives of Oral Biology",
issn = "0003-9969",
publisher = "Elsevier Limited",

}

Qualitative analysis on crystal growth of synthetic hydroxyapatite influenced by fluoride concentration. / Kang, Sumi; Seo, Jeong Taeg; Park, Sungho; Jung, Il Young; Lee, Chan Young; Park, Jeong Won.

In: Archives of Oral Biology, Vol. 104, 01.08.2019, p. 52-59.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Qualitative analysis on crystal growth of synthetic hydroxyapatite influenced by fluoride concentration

AU - Kang, Sumi

AU - Seo, Jeong Taeg

AU - Park, Sungho

AU - Jung, Il Young

AU - Lee, Chan Young

AU - Park, Jeong Won

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Objective: This study was designed to analyze the crystal growth of synthetic hydroxyapatite (HA) particles in pH 7.0 supersaturated solutions with different fluoride concentrations by FE-SEM, FE-TEM, X-ray diffraction (XRD), and FTIR. Design: Eight groups of pH 7.0 calcium phosphate supersaturated solutions were prepared with different fluoride concentrations (0, 1, 2, 4, 8, 16, 32, and 64 ppm). Each solution was introduced into the reactive column containing the synthetic HA for 48 h. The resulting products were prepared for FE-SEM, FE-TEM, XRD, and FTIR. Results: The FE-SEM examination revealed various morphological changes of the crystals, with additional, less-ordered crystallites in experimental solutions containing more than 8 ppm of fluoride. FE-TEM examination showed an additional amorphous layer on the surface of the crystals with the presence of fluoride, whereas definite lattice structures completely reached the surface of the crystals without fluorides. XRD data showed that all crystals had the same patterns as the unreacted synthetic HA, regardless of fluoride concentration. With FTIR results, the intensity of the OH-libration mode decreased when adding fluoride, compared to that of pristine HA. The resulting crystals were considered to be partially fluoridated HA under room temperature and pH 7.0 supersaturated solutions. Conclusion: Under the experimental conditions in this study, fluorides mainly react with the surface of the seed HA and have an impact on the growth of HA in a less effective manner as the concentration of fluoride increases.

AB - Objective: This study was designed to analyze the crystal growth of synthetic hydroxyapatite (HA) particles in pH 7.0 supersaturated solutions with different fluoride concentrations by FE-SEM, FE-TEM, X-ray diffraction (XRD), and FTIR. Design: Eight groups of pH 7.0 calcium phosphate supersaturated solutions were prepared with different fluoride concentrations (0, 1, 2, 4, 8, 16, 32, and 64 ppm). Each solution was introduced into the reactive column containing the synthetic HA for 48 h. The resulting products were prepared for FE-SEM, FE-TEM, XRD, and FTIR. Results: The FE-SEM examination revealed various morphological changes of the crystals, with additional, less-ordered crystallites in experimental solutions containing more than 8 ppm of fluoride. FE-TEM examination showed an additional amorphous layer on the surface of the crystals with the presence of fluoride, whereas definite lattice structures completely reached the surface of the crystals without fluorides. XRD data showed that all crystals had the same patterns as the unreacted synthetic HA, regardless of fluoride concentration. With FTIR results, the intensity of the OH-libration mode decreased when adding fluoride, compared to that of pristine HA. The resulting crystals were considered to be partially fluoridated HA under room temperature and pH 7.0 supersaturated solutions. Conclusion: Under the experimental conditions in this study, fluorides mainly react with the surface of the seed HA and have an impact on the growth of HA in a less effective manner as the concentration of fluoride increases.

UR - http://www.scopus.com/inward/record.url?scp=85066404778&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85066404778&partnerID=8YFLogxK

U2 - 10.1016/j.archoralbio.2019.05.022

DO - 10.1016/j.archoralbio.2019.05.022

M3 - Article

VL - 104

SP - 52

EP - 59

JO - Archives of Oral Biology

JF - Archives of Oral Biology

SN - 0003-9969

ER -