Quality assessment of meningioma radiomics studies: Bridging the gap between exploratory research and clinical applications

So Yeon Won, Yae Won Park, Sung Soo Ahn, Ju Hyung Moon, Eui Hyun Kim, Seok Gu Kang, Jong Hee Chang, Se Hoon Kim, Seung Koo Lee

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Purpose: To evaluate the quality of radiomics studies on meningiomas, using a radiomics quality score (RQS), Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD), and the Image Biomarker Standardization Initiative (IBSI). Methods: PubMed MEDLINE and Embase were searched to identify radiomics studies on meningiomas. Of 138 identified articles, 25 relevant original research articles were included. Studies were scored according to the RQS, TRIPOD guidelines, and items in IBSI. Results: Only four studies (16 %) performed external validation. The mean RQS was 5.6 out of 36 (15.4 %), and the basic adherence rate was 26.8 %. The adherence rate was low for stating biological correlation (4%), conducting calibration statistics (12 %), multiple segmentation (16 %), and stating potential clinical utility (16 %). None of the studies conducted a test‒retest or phantom study, stated a comparison to a ‘gold standard’, conducted prospective studies or cost-effectivity analysis, or opened code and data to the public, resulting in low RQS. The overall adherence rate for TRIPOD was 54.1 %, with low scores for reporting the title (4%), abstract (0%), blind assessment of the outcome (8%), and explaining the sample size (0%). According to IBSI items, only 6 (24 %), 6 (24 %), and 3 (12 %) studies performed N4 bias-field correction, isovoxel resampling, and grey-level discretization, respectively. No study performed skull stripping. Conclusion: The quality of radiomics studies for meningioma is insufficient. Acknowledgement of RQS, TRIPOD, and IBSI reporting guidelines may improve the quality of meningioma radiomics studies and enable their clinical application.

Original languageEnglish
Article number109673
JournalEuropean Journal of Radiology
Volume138
DOIs
Publication statusPublished - 2021 May

Bibliographical note

Funding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education ( 2020R1I1A1A01071648 ).

Publisher Copyright:
© 2021

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Fingerprint

Dive into the research topics of 'Quality assessment of meningioma radiomics studies: Bridging the gap between exploratory research and clinical applications'. Together they form a unique fingerprint.

Cite this