Quality of life patterns and its association with predictors among non-muscle invasive bladder cancer survivors: A latent profile analysis

Jeongok Park, Young Deuk Choi, Kyoungjin Lee, Miae Seo, Ahyoung Cho, Sejeong Lee, Keum hee Nam

Research output: Contribution to journalArticlepeer-review


Objective: This study identified group patterns in the quality of life (QOL), as well as examining factors associated with group membership, among non-muscle invasive bladder cancer (NMIBC) survivors. Methods: This was a cross-sectional study involving 278 participating NMIBC survivors. Mplus version 7.2 was used to perform the latent profile analysis of QOL using the EORTC QLQ-NMIBC-24. The participants’ social support, self-efficacy, knowledge level, depression, perceived severity of and susceptibility of cancer recurrence, and their demographic and clinical characteristics were compared between the subgroups, with a logistic regression analysis being adopted to examine the factors associated with the QOL subgroups. Results: The NMIBC survivors based on the QOL were classified into two subgroups: “QOL-high” (81.3%) and “QOL-low” (18.7%). Having ≥ 3 disease recurrences, perceived susceptibility toward and severity of cancer recurrence, and having depressive symptoms were significantly associated with the “QOL-low” group. Conclusions: Participants with frequent recurrences of NMIBC, higher perceived susceptibility and severity levels, and depressive symptoms had lower QOL. Therefore, it is necessary to develop intervention programs targeting participants with these characteristics to improve their QOL.

Original languageEnglish
Article number100063
JournalAsia-Pacific Journal of Oncology Nursing
Issue number6
Publication statusPublished - 2022 Jun

Bibliographical note

Funding Information:
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (Grant No. 2019R1F1A1062769 ) and (Grant No. 2020R1A6A1A03041989 ). This research was supported by the Brain Korea 21 FOUR Project funded by the NRF of Korea, Yonsei University College of Nursing (Grant No. F21JB7504007 ).

Publisher Copyright:
© 2022 The Authors

All Science Journal Classification (ASJC) codes

  • Oncology
  • Oncology(nursing)


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