Quality of Recovery of Patients Who Underwent Curative Pancreatectomy: Comparison of Total Intravenous Anesthesia Versus Inhalation Anesthesia Using the QOR-40 Questionnaire

Young Eun Joe, Chang Moo Kang, Hye Mi Lee, Ki Jun Kim, Ho Kyoung Hwang, Jeong Rim Lee

Research output: Contribution to journalArticlepeer-review

Abstract

Background: There has been increasing attention on the subjective recovery of patients undergoing cancer surgery. Total intravenous anesthesia (TIVA) and inhaled anesthesia with volatile anesthetics (INHA) are safe and common anesthetic techniques. Currently, TIVA and INHA have only been compared for less invasive and less complex surgeries. This prospective randomized trial aimed to compare the quality of recovery between TIVA and INHA in patients undergoing pancreatoduodenectomy (PD) or distal pancreatectomy (DP) using the Quality of Recovery (QOR)-40 questionnaire. Methods: We enrolled 132 patients who were randomly assigned to either the desflurane (DES) (INHA, balanced anesthesia with DES and remifentanil infusion) or TIVA (effect-site target-controlled infusion of propofol and remifentanil) groups and completed the QOR-40 questionnaire postoperatively. Results: The mean global QOR-40 score on postoperative day 3 was significantly higher in the TIVA group than in the DES group. In the PD group, the total QOR-40 score was significantly higher in the TIVA group than in the DES group. Moreover, the TIVA group had significantly higher scores in the physical comfort and psychological support QOR-40 dimensions than the DES group. Conclusion: TIVA provides better quality of recovery scores on POD 3 for patients undergoing curative pancreatectomy. Clinical trial registration number: NCT03447691

Original languageEnglish
Pages (from-to)2581-2590
Number of pages10
JournalWorld Journal of Surgery
Volume45
Issue number8
DOIs
Publication statusPublished - 2021 Aug

Bibliographical note

Funding Information:
This study was supported by Faculty Research Assistance Program of Yonsei University College of Medicine (No. 6-2017-0127).

Publisher Copyright:
© 2021, Société Internationale de Chirurgie.

All Science Journal Classification (ASJC) codes

  • Surgery

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