Quantification of cellular properties from external fields and resulting induced velocity: Magnetic susceptibility

Jeffrey J. Chalmers; Seungjoo Haam; Yang Zhao; Kara McCloskey; Lee Moore; Maciej Zborowski; P. Stephen Williams

doi:10.1002/(SICI)1097-0290(19990905)64:5<519::AID-BIT2>3.0.CO;2-V

Quantification of cellular properties from external fields and resulting induced velocity: Magnetic susceptibility

Jeffrey J. Chalmers, Seungjoo Haam, Yang Zhao, Kara McCloskey, Lee Moore, Maciej Zborowski, P. Stephen Williams

Department of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article

33 Citations (Scopus)

Abstract

An experimental technique is discussed in which the magnetic susceptibility of immunomagnetically labeled cells can be determined on a cell-by-cell basis. This technique is based on determining the magnetically induced velocity that an immunomagnetically labeled cell has in a well- defined magnetic energy gradient. This velocity is determined through the use of video recordings of microscopic images of cells moving in the magnetic energy gradient. These video images are then computer digitized and processed using a computer algorithm, cell tracking velocimetry, which allows larger numbers (>10³) of cells to be analyzed.

Original language	English
Pages (from-to)	519-526
Number of pages	8
Journal	Biotechnology and Bioengineering
Volume	64
Issue number	5
DOIs	https://doi.org/10.1002/(SICI)1097-0290(19990905)64:5<519::AID-BIT2>3.0.CO;2-V
Publication status	Published - 1999 Mar 20

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All Science Journal Classification (ASJC) codes

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

Cite this

Chalmers, J. J., Haam, S., Zhao, Y., McCloskey, K., Moore, L., Zborowski, M., & Williams, P. S. (1999). Quantification of cellular properties from external fields and resulting induced velocity: Magnetic susceptibility. Biotechnology and Bioengineering, 64(5), 519-526. https://doi.org/10.1002/(SICI)1097-0290(19990905)64:5<519::AID-BIT2>3.0.CO;2-V

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10.1002/(SICI)1097-0290(19990905)64:5<519::AID-BIT2>3.0.CO;2-V