Quantitative evaluation of vascularity using 2-D power doppler ultrasonography may not identify malignancy of the thyroid

Jung Hyun Yoon, Hyun Joo Shin, Eunkyung Kim, Hee Jung Moon, Yun Ho Roh, jinyoung kwak

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the usefulness of a quantitative vascular index in predicting thyroid malignancy. A total of 1309 thyroid nodules in 1257 patients (mean age: 50.2 y, range: 18-83 y) were included. The vascularity pattern and vascular index (VI) measured by quantification software for each nodule were obtained from 2-D power Doppler ultrasonography (US). Gray-scale US + vascularity pattern was compared with gray-scale US + VI with respect to diagnostic performance. Of the 1309 thyroid nodules, 927 (70.8%) were benign and 382 (29.2%) were malignant. The area under the receiver operating characteristics curve (Az) for gray-scale US (0.82) was significantly higher than that for US combined with vascularity pattern (0.77) or VI (0.70, all p < 0.001). Quantified VIs were higher in benign nodules, but did not improve the performance of 2-D US in diagnosing thyroid malignancy.

Original languageEnglish
Pages (from-to)2873-2883
Number of pages11
JournalUltrasound in Medicine and Biology
Volume41
Issue number11
DOIs
Publication statusPublished - 2015 Nov 1

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Doppler Ultrasonography
nodules
gray scale
Ultrasonography
Thyroid Gland
Blood Vessels
evaluation
Thyroid Nodule
Neoplasms
ROC Curve
receivers
computer programs
Software
curves

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics

Cite this

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abstract = "The purpose of this study was to evaluate the usefulness of a quantitative vascular index in predicting thyroid malignancy. A total of 1309 thyroid nodules in 1257 patients (mean age: 50.2 y, range: 18-83 y) were included. The vascularity pattern and vascular index (VI) measured by quantification software for each nodule were obtained from 2-D power Doppler ultrasonography (US). Gray-scale US + vascularity pattern was compared with gray-scale US + VI with respect to diagnostic performance. Of the 1309 thyroid nodules, 927 (70.8{\%}) were benign and 382 (29.2{\%}) were malignant. The area under the receiver operating characteristics curve (Az) for gray-scale US (0.82) was significantly higher than that for US combined with vascularity pattern (0.77) or VI (0.70, all p < 0.001). Quantified VIs were higher in benign nodules, but did not improve the performance of 2-D US in diagnosing thyroid malignancy.",
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Quantitative evaluation of vascularity using 2-D power doppler ultrasonography may not identify malignancy of the thyroid. / Yoon, Jung Hyun; Shin, Hyun Joo; Kim, Eunkyung; Moon, Hee Jung; Roh, Yun Ho; kwak, jinyoung.

In: Ultrasound in Medicine and Biology, Vol. 41, No. 11, 01.11.2015, p. 2873-2883.

Research output: Contribution to journalArticle

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