Quantitative light-induced fluorescence technology for quantitative evaluation of tooth wear

Sang Kyeom Kim, Hyung Suk Lee, Seok Woo Park, Eun Song Lee, Elbert De Josselin De Jong, Hoi In Jung, Baek Il Kim

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8 Citations (Scopus)


Various technologies used to objectively determine enamel thickness or dentin exposure have been suggested. However, most methods have clinical limitations. This study was conducted to confirm the potential of quantitative light-induced fluorescence (QLF) using autofluorescence intensity of occlusal surfaces of worn teeth according to enamel grinding depth in vitro. Sixteen permanent premolars were used. Each tooth was gradationally ground down at the occlusal surface in the apical direction. QLF-digital and swept-source optical coherence tomography images were acquired at each grinding depth (in steps of 100 μm). All QLF images were converted to 8-bit grayscale images to calculate the fluorescence intensity. The maximum brightness (MB) values of the same sound regions in grayscale images before (MBbaseline) and phased values after (MBworn) the grinding process were calculated. Finally, 13 samples were evaluated. MBworn increased over the grinding depth range with a strong correlation (r=0.994, P<0.001). In conclusion, the fluorescence intensity of the teeth and grinding depth was strongly correlated in the QLF images. Therefore, QLF technology may be a useful noninvasive tool used to monitor the progression of tooth wear and to conveniently estimate enamel thickness.

Original languageEnglish
Article number121701
JournalJournal of Biomedical Optics
Issue number12
Publication statusPublished - 2017 Dec 1

Bibliographical note

Funding Information:
Inspektor Research Systems BV provided the salary for author EdJdJ but did not have any additional role in the study design, data collection, analysis, decision to publish, or preparation of the paper. EdJdJ’s involvement in this research was under the auspices of his status as adjunct professor at Yonsei University College of Dentistry supported by Brain Pool Program and BK21 PLUS Project. The specific role of EdJdJ was to provide his expertise regarding the fluorescence technology. This does not alter the author’s adherence to the policies of the Journal of Biomedical Optics on sharing data and materials. EdJdJ holds several patents with respect to QLF technology. The remaining authors declared no conflicts of interest.

Funding Information:
This study was supported by a grant from the Korean Federation of Science and Technology Societies (KOFST) funded by the Korean Government (Ministry of Science, ICT and Future Planning, MSIP), and Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET) through High Value-added Food Technology Development Program, funded by Ministry of Agriculture, Food and Rural Affairs (MAFRA) (316071031HD020). Hoi-In Jung has contributed as a co-corresponding author with the corresponding author, Baek-Il Kim.

Publisher Copyright:
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE).

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering


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