Radical deoxygenation of alcohols and intermolecular carbon-carbon bond formation with surfactant-type radical chain carriers in water

Dae Hyan Cho, Doo Ok Jang

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

An efficient and mild method is developed for radical deoxygenation of alcohols and formation of carbon-carbon bonds in water without adding additives such as surfactants. The reaction was applied to synthesis of 2′,3′-didehydro-2′,3′-dideoxynucleosides that are potent anti-HIV agents. The reaction afforded environmentally benign reaction conditions.

Original languageEnglish
Pages (from-to)1799-1802
Number of pages4
JournalTetrahedron Letters
Volume46
Issue number11
DOIs
Publication statusPublished - 2005 Mar 14

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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