Radical deoxygenation of alcohols and vicinal diols with N-ethylpiperidine hypophosphite both in alcohols and in water is described. S-Methyl dithiocarbonate and bis-S-methyl dithiocarbonate of carbohydrates and nucleosides were deoxygenated efficiently under reaction conditions.
Bibliographical noteFunding Information:
This work was supported by grant (R05-2002-000-00036-0) from the basic research program of the Korea Science and Engineering Foundation.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry