Trifluoroacetates of tertiary alcohols undergo deoxygenation by Ph 2SiH2 in the presence of (tBuO)2 in excellent yields of the deoxy products without affecting the stereochemistry at β-carbon.
Bibliographical noteFunding Information:
This work was supported by Korea Research Foundation Grant (KRF-2002-015-CP0214).
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry