Radical isomerization via intramolecular ipso substitution of aryl ethers: Aryl translocation from oxygen to carbon

Lee Eun, Lee Chulbom, Sung Tae Jin, Sung Whang Ho, Sok Li Kap

Research output: Contribution to journalArticle

33 Citations (Scopus)


Bromopropyl aryl ethers an converted to 3-arylpropanols under standard radical generating conditions in the presence of tributylstannane and AIBN. This rearrangement involves intramolecular ipso attack of the alkyl radicals which generates spiro cyclohexadienyl radical intermediates.

Original languageEnglish
Pages (from-to)2343-2346
Number of pages4
JournalTetrahedron Letters
Issue number14
Publication statusPublished - 1993 Apr 2


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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