A method of preparing acid bromides directly from aldehydes with Br3CCO2Et under radical conditions was developed. Aromatic aldehydes with electron-donating group were found to be more reactive than aromatic aldehydes with electron-withdrawing group and aliphatic aldehydes under reaction conditions.
|Number of pages||3|
|Publication status||Published - 2007 Jan 8|
Bibliographical noteFunding Information:
This work was supported by joint research project under the KOSEF-NRCT cooperative program (F01-2004-000-10252-0) and CBMH.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry