Randomized controlled clinical trial comparing guided bone regeneration of peri-implant defects with soft-type block versus particulate bone substitutes: Six-month results of hard-tissue changes

Goran I. Benic, Stefan P. Bienz, Young Woo Song, Jae Kook Cha, Christoph H.F. Hämmerle, Ui Won Jung, Ronald E. Jung

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To test whether soft-type block bone substitute used for guided bone regeneration (GBR) of peri-implant defects leads to a different dimension of the augmented hard tissue than particulate bone substitute. Materials and Methods: In 40 patients, 40 two-piece dental implants were placed >2 months after tooth extraction. Following random allocation, 20 peri-implant bone dehiscences were grafted with a soft-type block made of synthetic biphasic calcium phosphate (BCP) + collagen and 20 bone dehiscences with particulate BCP. All the sites were covered with a collagen membrane stabilized with titanium pins. Immediately after wound closure and after 6 months, the horizontal dimension (HD) of the augmented hard tissue was measured at the level of implant shoulder using cone beam computed tomography. During re-entry at 6 months, the defect fill was clinically assessed. Results: At 6 months, the median HD measured 1.15 mm (mean: 1.31 mm) in the soft-block group and 0.93 mm (mean: 1.05 mm) in the particulate group (p =.6). At 6 months, 7.1% of contained defects and 61.9% of non-contained defects showed an incomplete vertical defect fill. Conclusions: Soft-type block of BCP + collagen used for GBR of peri-implant defects did not differ from particulate BCP regarding the dimension of the augmented hard tissue after 6 months of healing.

Original languageEnglish
Pages (from-to)480-495
Number of pages16
JournalJournal of Clinical Periodontology
Volume49
Issue number5
DOIs
Publication statusPublished - 2022 May

Bibliographical note

Funding Information:
We are grateful to Gisela M?ller (Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland) for support in manuscript preparation.

Funding Information:
The authors report no financial interests related to any products involved in this study. This study was supported by a research grant provided by Dentium, Seoul, South Korea, by the Department of Periodontology, Yonsei University College of Dentistry, Seoul, and by the Clinic of Reconstructive Dentistry, Center of Dental Medicine, University of Zurich, Switzerland.

Publisher Copyright:
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

All Science Journal Classification (ASJC) codes

  • Periodontics

Fingerprint

Dive into the research topics of 'Randomized controlled clinical trial comparing guided bone regeneration of peri-implant defects with soft-type block versus particulate bone substitutes: Six-month results of hard-tissue changes'. Together they form a unique fingerprint.

Cite this