Straightforward access to various 5- and 6-acylated naphtho[1,2-b]benzofurans was achieved by successive Sonogashira coupling and intramolecular alkyne carbonyl metathesis to assemble the central aromatic C ring of naphtho[1,2-b]benzofurans regiospecifically substituted with an acyl group at the C5 or C6 position.
Bibliographical noteFunding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (2014R1A2A1A11050491).
© Georg Thieme Verlag Stuttgart · New York-Synthesis 2017.
All Science Journal Classification (ASJC) codes
- Organic Chemistry