Relationship between blood mercury concentrations and serum γ-glutamyltranspeptidase level in Korean adults using data from the 2010 Korean National Health and Nutrition Examination Survey

Min Seok Seo, Hye Ree Lee, Jae Yong Shim, Hee Taik Kang, Yongjae Lee

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Mercury and serum γ-glutamyltranspeptidase (GGT) play an important role in anti-oxidant mechanisms. This study aimed to investigate the association between blood mercury concentrations and GGT in Korean men and women. Methods: A nationwide cross-sectional study was conducted to examine the relationship between blood mercury concentration and serum GGT among 1959 subjects (aged 20-87. y; 965 men, 994 women), using data from the 2010 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) for high GGT (≥. 75th percentile) for both men and women were calculated across blood mercury quartiles using multiple logistic regression analyses. Results: The mean values of BMI, waist circumference, diastolic blood pressure, total cholesterol, and triglycerides were highest in the highest quartile of blood mercury concentrations in both sexes. GGT levels gradually increased in accordance with blood mercury quartiles. Compared to the lowest quartile of blood mercury concentrations, the adjusted OR (95% CI) for high GGT of the highest quartile was 2.59 (1.51-4.43) in men and 2.03 (1.13-3.67) in women. Conclusion: We found a positive relationship between blood mercury concentration and serum GGT level in a representative population sample of Korean adults.

Original languageEnglish
Pages (from-to)160-163
Number of pages4
JournalClinica Chimica Acta
Volume430
DOIs
Publication statusPublished - 2014 Mar 20

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Nutrition Surveys
Nutrition
Mercury
Blood
Health
Serum
Odds Ratio
Confidence Intervals
Blood Pressure
Blood pressure
Waist Circumference
Oxidants
Logistics
Triglycerides
Cross-Sectional Studies
Logistic Models
Cholesterol
Regression Analysis

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

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title = "Relationship between blood mercury concentrations and serum γ-glutamyltranspeptidase level in Korean adults using data from the 2010 Korean National Health and Nutrition Examination Survey",
abstract = "Background: Mercury and serum γ-glutamyltranspeptidase (GGT) play an important role in anti-oxidant mechanisms. This study aimed to investigate the association between blood mercury concentrations and GGT in Korean men and women. Methods: A nationwide cross-sectional study was conducted to examine the relationship between blood mercury concentration and serum GGT among 1959 subjects (aged 20-87. y; 965 men, 994 women), using data from the 2010 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95{\%} confidence intervals (CIs) for high GGT (≥. 75th percentile) for both men and women were calculated across blood mercury quartiles using multiple logistic regression analyses. Results: The mean values of BMI, waist circumference, diastolic blood pressure, total cholesterol, and triglycerides were highest in the highest quartile of blood mercury concentrations in both sexes. GGT levels gradually increased in accordance with blood mercury quartiles. Compared to the lowest quartile of blood mercury concentrations, the adjusted OR (95{\%} CI) for high GGT of the highest quartile was 2.59 (1.51-4.43) in men and 2.03 (1.13-3.67) in women. Conclusion: We found a positive relationship between blood mercury concentration and serum GGT level in a representative population sample of Korean adults.",
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Relationship between blood mercury concentrations and serum γ-glutamyltranspeptidase level in Korean adults using data from the 2010 Korean National Health and Nutrition Examination Survey. / Seo, Min Seok; Lee, Hye Ree; Shim, Jae Yong; Kang, Hee Taik; Lee, Yongjae.

In: Clinica Chimica Acta, Vol. 430, 20.03.2014, p. 160-163.

Research output: Contribution to journalArticle

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AU - Seo, Min Seok

AU - Lee, Hye Ree

AU - Shim, Jae Yong

AU - Kang, Hee Taik

AU - Lee, Yongjae

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N2 - Background: Mercury and serum γ-glutamyltranspeptidase (GGT) play an important role in anti-oxidant mechanisms. This study aimed to investigate the association between blood mercury concentrations and GGT in Korean men and women. Methods: A nationwide cross-sectional study was conducted to examine the relationship between blood mercury concentration and serum GGT among 1959 subjects (aged 20-87. y; 965 men, 994 women), using data from the 2010 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) for high GGT (≥. 75th percentile) for both men and women were calculated across blood mercury quartiles using multiple logistic regression analyses. Results: The mean values of BMI, waist circumference, diastolic blood pressure, total cholesterol, and triglycerides were highest in the highest quartile of blood mercury concentrations in both sexes. GGT levels gradually increased in accordance with blood mercury quartiles. Compared to the lowest quartile of blood mercury concentrations, the adjusted OR (95% CI) for high GGT of the highest quartile was 2.59 (1.51-4.43) in men and 2.03 (1.13-3.67) in women. Conclusion: We found a positive relationship between blood mercury concentration and serum GGT level in a representative population sample of Korean adults.

AB - Background: Mercury and serum γ-glutamyltranspeptidase (GGT) play an important role in anti-oxidant mechanisms. This study aimed to investigate the association between blood mercury concentrations and GGT in Korean men and women. Methods: A nationwide cross-sectional study was conducted to examine the relationship between blood mercury concentration and serum GGT among 1959 subjects (aged 20-87. y; 965 men, 994 women), using data from the 2010 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) for high GGT (≥. 75th percentile) for both men and women were calculated across blood mercury quartiles using multiple logistic regression analyses. Results: The mean values of BMI, waist circumference, diastolic blood pressure, total cholesterol, and triglycerides were highest in the highest quartile of blood mercury concentrations in both sexes. GGT levels gradually increased in accordance with blood mercury quartiles. Compared to the lowest quartile of blood mercury concentrations, the adjusted OR (95% CI) for high GGT of the highest quartile was 2.59 (1.51-4.43) in men and 2.03 (1.13-3.67) in women. Conclusion: We found a positive relationship between blood mercury concentration and serum GGT level in a representative population sample of Korean adults.

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