Relationship between depression and lung function in the general population in Korea

A retrospective cross-sectional study

Youngmok Park, Ji Ye Jung, Young Sam Kim, Kyung Soo Chung, Joo Han Song, Song Yee Kim, Eun Young Kim, youngae kang, Moo Suk Park, Joon Chang, Ah Young Leem

Research output: Contribution to journalArticle

Abstract

Background: Lung function and depression are closely related to many chronic lung diseases. However, few studies have evaluated this association in the general population. In this study, we evaluated the relationship between lung function and depression in the general population in Korea. Participants and methods: Data from the Ansung–Ansan cohort, a community-based cohort in Korea, were used to analyze the relationships between depression and lung function parameters. A total of 3,321 men and women aged 40–69 years were enrolled. Spirometry data included the forced expiratory volume in 1 second (FEV 1 ), forced vital capacity (FVC), and the FEV 1 /FVC ratio. Depression was defined as a score of ≥16 by the Beck Depression Inventory (BDI). A propensity score analysis was conducted with the aim of reducing the bias of the retrospective study. Results: The overall prevalence of depression in the study population was 13.1% (434/3,321 participants). Depression was significantly more prevalent in women than in men (P<0.001) and in never smokers than in ever smokers (P<0.001). The group with depression was older (P<0.001) and had a lower average body mass index (BMI) (P=0.015) than the group without depression. The FEV 1 (P<0.001), FVC (P<0.001), and FEV 1 /FVC ratio (P=0.022) were significantly lower in the group with depression than in the group without depression. After adjusting for age, sex, BMI, and smoking status, the mean FEV 1 was lower in the group with a high BDI score than in the group with a low BDI score (P=0.044). Using multiple linear regression analysis and adjusting for covariates, no statistically significant relationship between lung function and the BDI score was found. However, the BDI score and FEV 1 were inversely related in subjects older than 50 years (P=0.023). Conclusion: Depression is associated with decreased lung function in the general population, especially in adults older than 50 years.

Original languageEnglish
Pages (from-to)2207-2213
Number of pages7
JournalInternational Journal of COPD
Volume13
DOIs
Publication statusPublished - 2018 Jan 1

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Korea
Cross-Sectional Studies
Depression
Lung
Population
Forced Expiratory Volume
Vital Capacity
Equipment and Supplies
Body Mass Index
Propensity Score
Spirometry
Lung Diseases
Linear Models
Chronic Disease

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

Park, Youngmok ; Jung, Ji Ye ; Kim, Young Sam ; Chung, Kyung Soo ; Song, Joo Han ; Kim, Song Yee ; Kim, Eun Young ; kang, youngae ; Park, Moo Suk ; Chang, Joon ; Leem, Ah Young. / Relationship between depression and lung function in the general population in Korea : A retrospective cross-sectional study. In: International Journal of COPD. 2018 ; Vol. 13. pp. 2207-2213.
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title = "Relationship between depression and lung function in the general population in Korea: A retrospective cross-sectional study",
abstract = "Background: Lung function and depression are closely related to many chronic lung diseases. However, few studies have evaluated this association in the general population. In this study, we evaluated the relationship between lung function and depression in the general population in Korea. Participants and methods: Data from the Ansung–Ansan cohort, a community-based cohort in Korea, were used to analyze the relationships between depression and lung function parameters. A total of 3,321 men and women aged 40–69 years were enrolled. Spirometry data included the forced expiratory volume in 1 second (FEV 1 ), forced vital capacity (FVC), and the FEV 1 /FVC ratio. Depression was defined as a score of ≥16 by the Beck Depression Inventory (BDI). A propensity score analysis was conducted with the aim of reducing the bias of the retrospective study. Results: The overall prevalence of depression in the study population was 13.1{\%} (434/3,321 participants). Depression was significantly more prevalent in women than in men (P<0.001) and in never smokers than in ever smokers (P<0.001). The group with depression was older (P<0.001) and had a lower average body mass index (BMI) (P=0.015) than the group without depression. The FEV 1 (P<0.001), FVC (P<0.001), and FEV 1 /FVC ratio (P=0.022) were significantly lower in the group with depression than in the group without depression. After adjusting for age, sex, BMI, and smoking status, the mean FEV 1 was lower in the group with a high BDI score than in the group with a low BDI score (P=0.044). Using multiple linear regression analysis and adjusting for covariates, no statistically significant relationship between lung function and the BDI score was found. However, the BDI score and FEV 1 were inversely related in subjects older than 50 years (P=0.023). Conclusion: Depression is associated with decreased lung function in the general population, especially in adults older than 50 years.",
author = "Youngmok Park and Jung, {Ji Ye} and Kim, {Young Sam} and Chung, {Kyung Soo} and Song, {Joo Han} and Kim, {Song Yee} and Kim, {Eun Young} and youngae kang and Park, {Moo Suk} and Joon Chang and Leem, {Ah Young}",
year = "2018",
month = "1",
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Park, Y, Jung, JY, Kim, YS, Chung, KS, Song, JH, Kim, SY, Kim, EY, kang, Y, Park, MS, Chang, J & Leem, AY 2018, 'Relationship between depression and lung function in the general population in Korea: A retrospective cross-sectional study', International Journal of COPD, vol. 13, pp. 2207-2213. https://doi.org/10.2147/COPD.S169025

Relationship between depression and lung function in the general population in Korea : A retrospective cross-sectional study. / Park, Youngmok; Jung, Ji Ye; Kim, Young Sam; Chung, Kyung Soo; Song, Joo Han; Kim, Song Yee; Kim, Eun Young; kang, youngae; Park, Moo Suk; Chang, Joon; Leem, Ah Young.

In: International Journal of COPD, Vol. 13, 01.01.2018, p. 2207-2213.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Relationship between depression and lung function in the general population in Korea

T2 - A retrospective cross-sectional study

AU - Park, Youngmok

AU - Jung, Ji Ye

AU - Kim, Young Sam

AU - Chung, Kyung Soo

AU - Song, Joo Han

AU - Kim, Song Yee

AU - Kim, Eun Young

AU - kang, youngae

AU - Park, Moo Suk

AU - Chang, Joon

AU - Leem, Ah Young

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: Lung function and depression are closely related to many chronic lung diseases. However, few studies have evaluated this association in the general population. In this study, we evaluated the relationship between lung function and depression in the general population in Korea. Participants and methods: Data from the Ansung–Ansan cohort, a community-based cohort in Korea, were used to analyze the relationships between depression and lung function parameters. A total of 3,321 men and women aged 40–69 years were enrolled. Spirometry data included the forced expiratory volume in 1 second (FEV 1 ), forced vital capacity (FVC), and the FEV 1 /FVC ratio. Depression was defined as a score of ≥16 by the Beck Depression Inventory (BDI). A propensity score analysis was conducted with the aim of reducing the bias of the retrospective study. Results: The overall prevalence of depression in the study population was 13.1% (434/3,321 participants). Depression was significantly more prevalent in women than in men (P<0.001) and in never smokers than in ever smokers (P<0.001). The group with depression was older (P<0.001) and had a lower average body mass index (BMI) (P=0.015) than the group without depression. The FEV 1 (P<0.001), FVC (P<0.001), and FEV 1 /FVC ratio (P=0.022) were significantly lower in the group with depression than in the group without depression. After adjusting for age, sex, BMI, and smoking status, the mean FEV 1 was lower in the group with a high BDI score than in the group with a low BDI score (P=0.044). Using multiple linear regression analysis and adjusting for covariates, no statistically significant relationship between lung function and the BDI score was found. However, the BDI score and FEV 1 were inversely related in subjects older than 50 years (P=0.023). Conclusion: Depression is associated with decreased lung function in the general population, especially in adults older than 50 years.

AB - Background: Lung function and depression are closely related to many chronic lung diseases. However, few studies have evaluated this association in the general population. In this study, we evaluated the relationship between lung function and depression in the general population in Korea. Participants and methods: Data from the Ansung–Ansan cohort, a community-based cohort in Korea, were used to analyze the relationships between depression and lung function parameters. A total of 3,321 men and women aged 40–69 years were enrolled. Spirometry data included the forced expiratory volume in 1 second (FEV 1 ), forced vital capacity (FVC), and the FEV 1 /FVC ratio. Depression was defined as a score of ≥16 by the Beck Depression Inventory (BDI). A propensity score analysis was conducted with the aim of reducing the bias of the retrospective study. Results: The overall prevalence of depression in the study population was 13.1% (434/3,321 participants). Depression was significantly more prevalent in women than in men (P<0.001) and in never smokers than in ever smokers (P<0.001). The group with depression was older (P<0.001) and had a lower average body mass index (BMI) (P=0.015) than the group without depression. The FEV 1 (P<0.001), FVC (P<0.001), and FEV 1 /FVC ratio (P=0.022) were significantly lower in the group with depression than in the group without depression. After adjusting for age, sex, BMI, and smoking status, the mean FEV 1 was lower in the group with a high BDI score than in the group with a low BDI score (P=0.044). Using multiple linear regression analysis and adjusting for covariates, no statistically significant relationship between lung function and the BDI score was found. However, the BDI score and FEV 1 were inversely related in subjects older than 50 years (P=0.023). Conclusion: Depression is associated with decreased lung function in the general population, especially in adults older than 50 years.

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JF - International Journal of COPD

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