Low paraoxonase-1 (PON1) activity has been regarded as one of risk factors for cardiovascular disease. We showed that low PON1 activity was independently associated with carotid intima-media thickness (IMT) and heart to femoral pulse wave velocity (hfPWV) in hypertensive patients. Our results indicate that PON1 activity may reflect early structural and functional changes of arteries in this population.
Bibliographical noteFunding Information:
This study was supported by a grant (A000385) from the Ministry of Health and Welfare, Republic of Korea, a grant from the Seoul R&BD Program, Republic of Korea (10526) and a grant from the Korean Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A085136).
All Science Journal Classification (ASJC) codes
- Internal Medicine