Relationship between serum ferritin level and blood mercury concentration using data from the Korean national health and nutrition examination survey (2010-2012)

Yongjae Lee, In Cheol Hwang

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1 Citation (Scopus)

Abstract

Background: Studies on the association between serum ferritin levels (S-Ft) and blood mercury concentrations (B-Hg) are scarce. The objective of this study was to investigate the relationships between these two parameters using a large-scale nationwide representative sample of the Korean males.Method: A nationwide cross-sectional study was conducted to examine the relationship between S-Ft and B-Hg in 2832 men over 19 years of age (aged 20-87 years), using data from the 2010-2012 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) for high B-Hg (>75th percentile) were calculated across S-Ft quartiles using multiple logistic regression analyses.Results: Mean values of B-Hg gradually increased in accordance with the quartiles of S-Ft (P-trend<0.001). The odds ratio (95% CI) for high B-Hg with the doubling of S-Ft was 1.51 (1.25-1.84) after adjusting for age, fish/shellfish consumption, rice consumption, waist circumference, cigarette smoking, alcohol intake, regular exercise, blood pressure, fasting plasma glucose, triglyceride, and high-density lipoprotein cholesterol. Compared with the lowest quartiles of B-Hg, the ORs (95% CI) for high S-Ft in the 3rd and 4th quartiles were 2.09 (1.17-3.73) and 2.73 (1.55-4.79) after adjusting for the same co-variables.Conclusion: We found a positive relationship between S-Ft and B-Hg in a representative population sample of Korean adult men. Our results suggested S-Ft as a tool for environmental Hg exposure assessment.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalEnvironmental Research
Volume135
DOIs
Publication statusPublished - 2014 Nov 1

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health and nutrition
Nutrition Surveys
Ferritins
Nutrition
Mercury
serum
Blood
blood
Health
Serum
confidence interval
Odds Ratio
Confidence Intervals
Shellfish
fasting
mercury
Blood pressure
Environmental Exposure
Waist Circumference
shellfish

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Environmental Science(all)

Cite this

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title = "Relationship between serum ferritin level and blood mercury concentration using data from the Korean national health and nutrition examination survey (2010-2012)",
abstract = "Background: Studies on the association between serum ferritin levels (S-Ft) and blood mercury concentrations (B-Hg) are scarce. The objective of this study was to investigate the relationships between these two parameters using a large-scale nationwide representative sample of the Korean males.Method: A nationwide cross-sectional study was conducted to examine the relationship between S-Ft and B-Hg in 2832 men over 19 years of age (aged 20-87 years), using data from the 2010-2012 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95{\%} confidence intervals (CIs) for high B-Hg (>75th percentile) were calculated across S-Ft quartiles using multiple logistic regression analyses.Results: Mean values of B-Hg gradually increased in accordance with the quartiles of S-Ft (P-trend<0.001). The odds ratio (95{\%} CI) for high B-Hg with the doubling of S-Ft was 1.51 (1.25-1.84) after adjusting for age, fish/shellfish consumption, rice consumption, waist circumference, cigarette smoking, alcohol intake, regular exercise, blood pressure, fasting plasma glucose, triglyceride, and high-density lipoprotein cholesterol. Compared with the lowest quartiles of B-Hg, the ORs (95{\%} CI) for high S-Ft in the 3rd and 4th quartiles were 2.09 (1.17-3.73) and 2.73 (1.55-4.79) after adjusting for the same co-variables.Conclusion: We found a positive relationship between S-Ft and B-Hg in a representative population sample of Korean adult men. Our results suggested S-Ft as a tool for environmental Hg exposure assessment.",
author = "Yongjae Lee and Hwang, {In Cheol}",
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language = "English",
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journal = "Environmental Research",
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AU - Lee, Yongjae

AU - Hwang, In Cheol

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N2 - Background: Studies on the association between serum ferritin levels (S-Ft) and blood mercury concentrations (B-Hg) are scarce. The objective of this study was to investigate the relationships between these two parameters using a large-scale nationwide representative sample of the Korean males.Method: A nationwide cross-sectional study was conducted to examine the relationship between S-Ft and B-Hg in 2832 men over 19 years of age (aged 20-87 years), using data from the 2010-2012 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) for high B-Hg (>75th percentile) were calculated across S-Ft quartiles using multiple logistic regression analyses.Results: Mean values of B-Hg gradually increased in accordance with the quartiles of S-Ft (P-trend<0.001). The odds ratio (95% CI) for high B-Hg with the doubling of S-Ft was 1.51 (1.25-1.84) after adjusting for age, fish/shellfish consumption, rice consumption, waist circumference, cigarette smoking, alcohol intake, regular exercise, blood pressure, fasting plasma glucose, triglyceride, and high-density lipoprotein cholesterol. Compared with the lowest quartiles of B-Hg, the ORs (95% CI) for high S-Ft in the 3rd and 4th quartiles were 2.09 (1.17-3.73) and 2.73 (1.55-4.79) after adjusting for the same co-variables.Conclusion: We found a positive relationship between S-Ft and B-Hg in a representative population sample of Korean adult men. Our results suggested S-Ft as a tool for environmental Hg exposure assessment.

AB - Background: Studies on the association between serum ferritin levels (S-Ft) and blood mercury concentrations (B-Hg) are scarce. The objective of this study was to investigate the relationships between these two parameters using a large-scale nationwide representative sample of the Korean males.Method: A nationwide cross-sectional study was conducted to examine the relationship between S-Ft and B-Hg in 2832 men over 19 years of age (aged 20-87 years), using data from the 2010-2012 Korean National Health and Nutrition Examination Survey. The odds ratios (ORs) and 95% confidence intervals (CIs) for high B-Hg (>75th percentile) were calculated across S-Ft quartiles using multiple logistic regression analyses.Results: Mean values of B-Hg gradually increased in accordance with the quartiles of S-Ft (P-trend<0.001). The odds ratio (95% CI) for high B-Hg with the doubling of S-Ft was 1.51 (1.25-1.84) after adjusting for age, fish/shellfish consumption, rice consumption, waist circumference, cigarette smoking, alcohol intake, regular exercise, blood pressure, fasting plasma glucose, triglyceride, and high-density lipoprotein cholesterol. Compared with the lowest quartiles of B-Hg, the ORs (95% CI) for high S-Ft in the 3rd and 4th quartiles were 2.09 (1.17-3.73) and 2.73 (1.55-4.79) after adjusting for the same co-variables.Conclusion: We found a positive relationship between S-Ft and B-Hg in a representative population sample of Korean adult men. Our results suggested S-Ft as a tool for environmental Hg exposure assessment.

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