Relationship between visceral adiposity and bone mineral density in korean adults

Han Seok Choi, Kwang Joon Kim, Kyoung Min Kim, Nam Wook Hur, Yumie Rhee, Dae Suk Han, Eunjig Lee, Sungkil Lim

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The objective of the study was to investigate the relationship between visceral and subcutaneous adiposity measured by computed tomography and bone mineral density (BMD) and to identify the metabolic factors associated with BMD. We studied 461 subjects recruited from the health-care center at Severance Hospital, Yonsei University College of Medicine. Multivariate regression analyses were conducted to examine the cross-sectional associations between body composition-related or metabolic parameters and BMD. After adjusting for body weight and other confounders, visceral fat area had an inverse association with BMD in men (β = -0.133, P = 0.049 for lumbar spine; β = -0.135, P = 0.037 for femoral neck; β = -0.179, P = 0.005 for total hip) and women (β = -0.424, P < 0.001 for lumbar spine; β = -0.302, P = 0.005 for femoral neck; β = -0.274, P = 0.014 for total hip). However, the subcutaneous fat area showed no statistically significant relationship with BMD at most sites. Among the metabolic parameters, HDL cholesterol was positively associated with BMD, while LDL cholesterol was negatively associated with BMD in men. In women, total and LDL cholesterol were negatively associated with BMD at the lumbar spine. We conclude that visceral adiposity is inversely associated with BMD after adjusting for confounders and that metabolic factors may partly contribute to this inverse relation.

Original languageEnglish
Pages (from-to)218-225
Number of pages8
JournalCalcified Tissue International
Volume87
Issue number3
DOIs
Publication statusPublished - 2010 Sep 1

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Adiposity
Bone Density
Spine
Femur Neck
LDL Cholesterol
Hip
Intra-Abdominal Fat
Subcutaneous Fat
Body Composition
HDL Cholesterol
Multivariate Analysis
Tomography
Body Weight
Regression Analysis
Medicine
Delivery of Health Care

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Orthopedics and Sports Medicine
  • Endocrinology

Cite this

Choi, Han Seok ; Kim, Kwang Joon ; Kim, Kyoung Min ; Hur, Nam Wook ; Rhee, Yumie ; Han, Dae Suk ; Lee, Eunjig ; Lim, Sungkil. / Relationship between visceral adiposity and bone mineral density in korean adults. In: Calcified Tissue International. 2010 ; Vol. 87, No. 3. pp. 218-225.
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Relationship between visceral adiposity and bone mineral density in korean adults. / Choi, Han Seok; Kim, Kwang Joon; Kim, Kyoung Min; Hur, Nam Wook; Rhee, Yumie; Han, Dae Suk; Lee, Eunjig; Lim, Sungkil.

In: Calcified Tissue International, Vol. 87, No. 3, 01.09.2010, p. 218-225.

Research output: Contribution to journalArticle

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