Release characteristics of ibuprofen from excipient-loaded alginate gel beads

Sung Joo Hwang; Gye Ju Rhee; Ki Myung Lee; Kyoung Hee Oh; Chong Kook Kim

doi:10.1016/0378-5173(94)00281-9

Release characteristics of ibuprofen from excipient-loaded alginate gel beads

Sung Joo Hwang, Gye Ju Rhee, Ki Myung Lee, Kyoung Hee Oh, Chong Kook Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Ibuprofen-loaded alginate beads were prepared and found to optimize in vitro release with zero-order kinetics. The release of ibuprofen could be controlled by adding excipients or by adjusting the NaAlg/ibuprofen ratio.

Original language	English
Pages (from-to)	125-128
Number of pages	4
Journal	International Journal of Pharmaceutics
Volume	116
Issue number	1
DOIs	https://doi.org/10.1016/0378-5173(94)00281-9
Publication status	Published - 1995 Mar 14

Bibliographical note

Funding Information:
This work was supportedb y a researchg rant from the Institute of Medicinal Development, College of PharmacyC, hungnamN ationalUni-versitya nd from the ResearchC enterfor New Drug DevelopmenSt,e oulN ationalU niversity.

All Science Journal Classification (ASJC) codes

Pharmaceutical Science

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10.1016/0378-5173(94)00281-9

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title = "Release characteristics of ibuprofen from excipient-loaded alginate gel beads",

abstract = "Ibuprofen-loaded alginate beads were prepared and found to optimize in vitro release with zero-order kinetics. The release of ibuprofen could be controlled by adding excipients or by adjusting the NaAlg/ibuprofen ratio.",

author = "Hwang, {Sung Joo} and Rhee, {Gye Ju} and Lee, {Ki Myung} and Oh, {Kyoung Hee} and Kim, {Chong Kook}",

note = "Funding Information: This work was supportedb y a researchg rant from the Institute of Medicinal Development, College of PharmacyC, hungnamN ationalUni-versitya nd from the ResearchC enterfor New Drug DevelopmenSt,e oulN ationalU niversity.",

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AU - Rhee, Gye Ju

AU - Lee, Ki Myung

AU - Oh, Kyoung Hee

AU - Kim, Chong Kook

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AB - Ibuprofen-loaded alginate beads were prepared and found to optimize in vitro release with zero-order kinetics. The release of ibuprofen could be controlled by adding excipients or by adjusting the NaAlg/ibuprofen ratio.

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