Abstract
Purpose: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients. Methods: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-guided biopsy were included. Results: Of the 53 BI-RADS category 4 and 5 lesions, eight (15.1%) were malignant (six ductal carcinomas in situ, one invasive ductal carcinoma, and one solid papillary carcinoma). There was no malignancy among the remaining 14 category 3 lesions. Malignant lesions more frequently displayed a round or irregular shape (75.0%, 6/8; p= 0.030) and nonparallel orientation (33.3%, 4/12; p= 0.029) compared to the benign lesions. The increase in the BI-RADS category corresponded with a rise in the malignancy rate (p= 0.004). Conclusion: The BI-RADS lexicon and final assessment of breast US reliably detect and characterize malignancy in mammographically negative patients with pathologic nipple discharge.
| Original language | English |
|---|---|
| Pages (from-to) | 308-315 |
| Number of pages | 8 |
| Journal | Journal of Breast Cancer |
| Volume | 19 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2016 Sep |
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All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research
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Reliability of breast ultrasound BI-RADS final assessment in mammographically negative patients with nipple discharge and radiologic predictors of malignancy. / Park, Chae Jung; Kim, Eun Kyung; Moon, Hee Jung; Yoon, Jung Hyun; Kim, Min Jung.
In: Journal of Breast Cancer, Vol. 19, No. 3, 09.2016, p. 308-315.Research output: Contribution to journal › Article
TY - JOUR
T1 - Reliability of breast ultrasound BI-RADS final assessment in mammographically negative patients with nipple discharge and radiologic predictors of malignancy
AU - Park, Chae Jung
AU - Kim, Eun Kyung
AU - Moon, Hee Jung
AU - Yoon, Jung Hyun
AU - Kim, Min Jung
PY - 2016/9
Y1 - 2016/9
N2 - Purpose: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients. Methods: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-guided biopsy were included. Results: Of the 53 BI-RADS category 4 and 5 lesions, eight (15.1%) were malignant (six ductal carcinomas in situ, one invasive ductal carcinoma, and one solid papillary carcinoma). There was no malignancy among the remaining 14 category 3 lesions. Malignant lesions more frequently displayed a round or irregular shape (75.0%, 6/8; p= 0.030) and nonparallel orientation (33.3%, 4/12; p= 0.029) compared to the benign lesions. The increase in the BI-RADS category corresponded with a rise in the malignancy rate (p= 0.004). Conclusion: The BI-RADS lexicon and final assessment of breast US reliably detect and characterize malignancy in mammographically negative patients with pathologic nipple discharge.
AB - Purpose: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients. Methods: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-guided biopsy were included. Results: Of the 53 BI-RADS category 4 and 5 lesions, eight (15.1%) were malignant (six ductal carcinomas in situ, one invasive ductal carcinoma, and one solid papillary carcinoma). There was no malignancy among the remaining 14 category 3 lesions. Malignant lesions more frequently displayed a round or irregular shape (75.0%, 6/8; p= 0.030) and nonparallel orientation (33.3%, 4/12; p= 0.029) compared to the benign lesions. The increase in the BI-RADS category corresponded with a rise in the malignancy rate (p= 0.004). Conclusion: The BI-RADS lexicon and final assessment of breast US reliably detect and characterize malignancy in mammographically negative patients with pathologic nipple discharge.
UR - http://www.scopus.com/inward/record.url?scp=84992145886&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84992145886&partnerID=8YFLogxK
U2 - 10.4048/jbc.2016.19.3.308
DO - 10.4048/jbc.2016.19.3.308
M3 - Article
AN - SCOPUS:84992145886
VL - 19
SP - 308
EP - 315
JO - Journal of Breast Cancer
JF - Journal of Breast Cancer
SN - 1738-6756
IS - 3
ER -