Remineralization potential of new toothpaste containing nano-hydroxyapatite

S. H. Jeong, S. O. Jang, K. N. Kim, H. K. Kwon, Y. D. Park, B. I. Kim

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Hydroxyapatite is the main component of enamel that gives the tooth a bright white appearance and eliminates the diffused reflection of light by filling up the fine pores of the tooth surface. Accordingly, remineralization of the teeth can be expected to some extent if hydroxyapatite is used to treat an incipient caries lesion (early white spot lesion). In addition, the remineralization effect will be increased if the particle size of hydroxyapatite can be reduced to less than that of the micron-size in existing toothpaste preparations. The aim of this in vitro study was to evaluate the effect of nano-hydroxyapatite toothpaste, which was produced by nano-technology, on the remineralization of human enamel. A tooth specimen, on which artificial incipient caries had been induced, was immersed into two toothpaste slurries for remineralization. One contains nano-sized hydroxyapatite and fluoride, and the other contains nano-sized hydroxyapatite excluding fluoride. In order to evaluate the remineralization effect, the Vickers Hardness Number & SEM image of the enamel surface was evaluated at each step. There were significant differences in VHN values between those obtained before and after the remineralization steps. The results showed that the remineralization effect increased with increasing immersing time (P<0.05). However, there were no significant differences in VHN values between the two groups (P>0.05). SEM also demonstrated differences the in micro surface at each step. In conclusion, a toothpaste containing nano-sized hydroxyapatite has the potential to remineralize an incipient caries lesion. In addition, the addition of fluoride had no synergistic effect on remineralization.

Original languageEnglish
Pages (from-to)537-540
Number of pages4
JournalKey Engineering Materials
Volume309-311 I
Publication statusPublished - 2006 Apr 6

Fingerprint

Toothpastes
Durapatite
Hydroxyapatite
Enamels
Fluorides
Scanning electron microscopy
Vickers hardness
Slurries
Nanotechnology
Particle size

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

Cite this

Jeong, S. H., Jang, S. O., Kim, K. N., Kwon, H. K., Park, Y. D., & Kim, B. I. (2006). Remineralization potential of new toothpaste containing nano-hydroxyapatite. Key Engineering Materials, 309-311 I, 537-540.
Jeong, S. H. ; Jang, S. O. ; Kim, K. N. ; Kwon, H. K. ; Park, Y. D. ; Kim, B. I. / Remineralization potential of new toothpaste containing nano-hydroxyapatite. In: Key Engineering Materials. 2006 ; Vol. 309-311 I. pp. 537-540.
@article{fdf189b7a6f54207ab00085d95ad1fb9,
title = "Remineralization potential of new toothpaste containing nano-hydroxyapatite",
abstract = "Hydroxyapatite is the main component of enamel that gives the tooth a bright white appearance and eliminates the diffused reflection of light by filling up the fine pores of the tooth surface. Accordingly, remineralization of the teeth can be expected to some extent if hydroxyapatite is used to treat an incipient caries lesion (early white spot lesion). In addition, the remineralization effect will be increased if the particle size of hydroxyapatite can be reduced to less than that of the micron-size in existing toothpaste preparations. The aim of this in vitro study was to evaluate the effect of nano-hydroxyapatite toothpaste, which was produced by nano-technology, on the remineralization of human enamel. A tooth specimen, on which artificial incipient caries had been induced, was immersed into two toothpaste slurries for remineralization. One contains nano-sized hydroxyapatite and fluoride, and the other contains nano-sized hydroxyapatite excluding fluoride. In order to evaluate the remineralization effect, the Vickers Hardness Number & SEM image of the enamel surface was evaluated at each step. There were significant differences in VHN values between those obtained before and after the remineralization steps. The results showed that the remineralization effect increased with increasing immersing time (P<0.05). However, there were no significant differences in VHN values between the two groups (P>0.05). SEM also demonstrated differences the in micro surface at each step. In conclusion, a toothpaste containing nano-sized hydroxyapatite has the potential to remineralize an incipient caries lesion. In addition, the addition of fluoride had no synergistic effect on remineralization.",
author = "Jeong, {S. H.} and Jang, {S. O.} and Kim, {K. N.} and Kwon, {H. K.} and Park, {Y. D.} and Kim, {B. I.}",
year = "2006",
month = "4",
day = "6",
language = "English",
volume = "309-311 I",
pages = "537--540",
journal = "Key Engineering Materials",
issn = "1013-9826",
publisher = "Trans Tech Publications",

}

Jeong, SH, Jang, SO, Kim, KN, Kwon, HK, Park, YD & Kim, BI 2006, 'Remineralization potential of new toothpaste containing nano-hydroxyapatite', Key Engineering Materials, vol. 309-311 I, pp. 537-540.

Remineralization potential of new toothpaste containing nano-hydroxyapatite. / Jeong, S. H.; Jang, S. O.; Kim, K. N.; Kwon, H. K.; Park, Y. D.; Kim, B. I.

In: Key Engineering Materials, Vol. 309-311 I, 06.04.2006, p. 537-540.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Remineralization potential of new toothpaste containing nano-hydroxyapatite

AU - Jeong, S. H.

AU - Jang, S. O.

AU - Kim, K. N.

AU - Kwon, H. K.

AU - Park, Y. D.

AU - Kim, B. I.

PY - 2006/4/6

Y1 - 2006/4/6

N2 - Hydroxyapatite is the main component of enamel that gives the tooth a bright white appearance and eliminates the diffused reflection of light by filling up the fine pores of the tooth surface. Accordingly, remineralization of the teeth can be expected to some extent if hydroxyapatite is used to treat an incipient caries lesion (early white spot lesion). In addition, the remineralization effect will be increased if the particle size of hydroxyapatite can be reduced to less than that of the micron-size in existing toothpaste preparations. The aim of this in vitro study was to evaluate the effect of nano-hydroxyapatite toothpaste, which was produced by nano-technology, on the remineralization of human enamel. A tooth specimen, on which artificial incipient caries had been induced, was immersed into two toothpaste slurries for remineralization. One contains nano-sized hydroxyapatite and fluoride, and the other contains nano-sized hydroxyapatite excluding fluoride. In order to evaluate the remineralization effect, the Vickers Hardness Number & SEM image of the enamel surface was evaluated at each step. There were significant differences in VHN values between those obtained before and after the remineralization steps. The results showed that the remineralization effect increased with increasing immersing time (P<0.05). However, there were no significant differences in VHN values between the two groups (P>0.05). SEM also demonstrated differences the in micro surface at each step. In conclusion, a toothpaste containing nano-sized hydroxyapatite has the potential to remineralize an incipient caries lesion. In addition, the addition of fluoride had no synergistic effect on remineralization.

AB - Hydroxyapatite is the main component of enamel that gives the tooth a bright white appearance and eliminates the diffused reflection of light by filling up the fine pores of the tooth surface. Accordingly, remineralization of the teeth can be expected to some extent if hydroxyapatite is used to treat an incipient caries lesion (early white spot lesion). In addition, the remineralization effect will be increased if the particle size of hydroxyapatite can be reduced to less than that of the micron-size in existing toothpaste preparations. The aim of this in vitro study was to evaluate the effect of nano-hydroxyapatite toothpaste, which was produced by nano-technology, on the remineralization of human enamel. A tooth specimen, on which artificial incipient caries had been induced, was immersed into two toothpaste slurries for remineralization. One contains nano-sized hydroxyapatite and fluoride, and the other contains nano-sized hydroxyapatite excluding fluoride. In order to evaluate the remineralization effect, the Vickers Hardness Number & SEM image of the enamel surface was evaluated at each step. There were significant differences in VHN values between those obtained before and after the remineralization steps. The results showed that the remineralization effect increased with increasing immersing time (P<0.05). However, there were no significant differences in VHN values between the two groups (P>0.05). SEM also demonstrated differences the in micro surface at each step. In conclusion, a toothpaste containing nano-sized hydroxyapatite has the potential to remineralize an incipient caries lesion. In addition, the addition of fluoride had no synergistic effect on remineralization.

UR - http://www.scopus.com/inward/record.url?scp=33645452025&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645452025&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33645452025

VL - 309-311 I

SP - 537

EP - 540

JO - Key Engineering Materials

JF - Key Engineering Materials

SN - 1013-9826

ER -

Jeong SH, Jang SO, Kim KN, Kwon HK, Park YD, Kim BI. Remineralization potential of new toothpaste containing nano-hydroxyapatite. Key Engineering Materials. 2006 Apr 6;309-311 I:537-540.