Retention and Healing Outcomes after Intentional Replantation

Sin Yeon Cho, Yoon Lee, Su Jung Shin, EuiSeong Kim, Il Young Jung, Shimon Friedman, Seung Jong Lee

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Introduction Intentional replantation is an alternative to tooth extraction and prosthetic replacement when conventional endodontic treatment modalities are unfeasible or contraindicated. This study assessed tooth retention and healing after intentional replantation and explored predictors of these outcomes. Methods Data of intentional replantation procedures performed between March 2000 and December 2010 were collected prospectively, excluding teeth with preoperative periodontal and root defects. A cohort of 159 teeth was followed up for 0.5-12 years. Retention and healed status without complications (periapical radiolucency, external root resorption, ankylosis, signs/symptoms, probing ≥6 mm) was recorded and analyzed with Kaplan-Meier survival analysis and Cox proportional hazard regression model (P <.05). Results Complications leading to extraction occurred in 8 of 159 teeth (5%). Kaplan-Meier survival function suggested 93% cumulative 12-year retention. Cumulative healed rates declined from 91% at 6 months to 77% at 3 years. The healed rate was significantly lower for maxillary teeth without preoperative periapical radiolucency, replanted in more than 15 minutes, and root-end filled with ProRoot MTA. Cox regression identified extraoral time ≤15 minutes as predictor of complication-free healing (P <.04; hazard ratio, 2.767; 95% confidence interval, 1.053-7.272). Conclusions This prospective cohort study of contemporary intentional replantation suggested a cumulative 12-year retention rate of 93% and healed rate of 77% after 3 years. Healing occurred 1.7 times more frequently in teeth replanted within 15 minutes. Although most complications occurred within 1 year after replantation, follow-up should extend for at least 3 years to capture late complications.

Original languageEnglish
Pages (from-to)909-915
Number of pages7
JournalJournal of Endodontics
Volume42
Issue number6
DOIs
Publication statusPublished - 2016 Jun 1

Fingerprint

Replantation
Tooth
Pemetrexed
Root Resorption
Ankylosis
Tooth Extraction
Endodontics
Kaplan-Meier Estimate
Survival Analysis
Proportional Hazards Models
Signs and Symptoms
Cohort Studies
Prospective Studies
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

Cho, Sin Yeon ; Lee, Yoon ; Shin, Su Jung ; Kim, EuiSeong ; Jung, Il Young ; Friedman, Shimon ; Lee, Seung Jong. / Retention and Healing Outcomes after Intentional Replantation. In: Journal of Endodontics. 2016 ; Vol. 42, No. 6. pp. 909-915.
@article{636de06a55494cd1a595288d9444db04,
title = "Retention and Healing Outcomes after Intentional Replantation",
abstract = "Introduction Intentional replantation is an alternative to tooth extraction and prosthetic replacement when conventional endodontic treatment modalities are unfeasible or contraindicated. This study assessed tooth retention and healing after intentional replantation and explored predictors of these outcomes. Methods Data of intentional replantation procedures performed between March 2000 and December 2010 were collected prospectively, excluding teeth with preoperative periodontal and root defects. A cohort of 159 teeth was followed up for 0.5-12 years. Retention and healed status without complications (periapical radiolucency, external root resorption, ankylosis, signs/symptoms, probing ≥6 mm) was recorded and analyzed with Kaplan-Meier survival analysis and Cox proportional hazard regression model (P <.05). Results Complications leading to extraction occurred in 8 of 159 teeth (5{\%}). Kaplan-Meier survival function suggested 93{\%} cumulative 12-year retention. Cumulative healed rates declined from 91{\%} at 6 months to 77{\%} at 3 years. The healed rate was significantly lower for maxillary teeth without preoperative periapical radiolucency, replanted in more than 15 minutes, and root-end filled with ProRoot MTA. Cox regression identified extraoral time ≤15 minutes as predictor of complication-free healing (P <.04; hazard ratio, 2.767; 95{\%} confidence interval, 1.053-7.272). Conclusions This prospective cohort study of contemporary intentional replantation suggested a cumulative 12-year retention rate of 93{\%} and healed rate of 77{\%} after 3 years. Healing occurred 1.7 times more frequently in teeth replanted within 15 minutes. Although most complications occurred within 1 year after replantation, follow-up should extend for at least 3 years to capture late complications.",
author = "Cho, {Sin Yeon} and Yoon Lee and Shin, {Su Jung} and EuiSeong Kim and Jung, {Il Young} and Shimon Friedman and Lee, {Seung Jong}",
year = "2016",
month = "6",
day = "1",
doi = "10.1016/j.joen.2016.03.006",
language = "English",
volume = "42",
pages = "909--915",
journal = "Journal of Endodontics",
issn = "0099-2399",
publisher = "Elsevier Inc.",
number = "6",

}

Retention and Healing Outcomes after Intentional Replantation. / Cho, Sin Yeon; Lee, Yoon; Shin, Su Jung; Kim, EuiSeong; Jung, Il Young; Friedman, Shimon; Lee, Seung Jong.

In: Journal of Endodontics, Vol. 42, No. 6, 01.06.2016, p. 909-915.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Retention and Healing Outcomes after Intentional Replantation

AU - Cho, Sin Yeon

AU - Lee, Yoon

AU - Shin, Su Jung

AU - Kim, EuiSeong

AU - Jung, Il Young

AU - Friedman, Shimon

AU - Lee, Seung Jong

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Introduction Intentional replantation is an alternative to tooth extraction and prosthetic replacement when conventional endodontic treatment modalities are unfeasible or contraindicated. This study assessed tooth retention and healing after intentional replantation and explored predictors of these outcomes. Methods Data of intentional replantation procedures performed between March 2000 and December 2010 were collected prospectively, excluding teeth with preoperative periodontal and root defects. A cohort of 159 teeth was followed up for 0.5-12 years. Retention and healed status without complications (periapical radiolucency, external root resorption, ankylosis, signs/symptoms, probing ≥6 mm) was recorded and analyzed with Kaplan-Meier survival analysis and Cox proportional hazard regression model (P <.05). Results Complications leading to extraction occurred in 8 of 159 teeth (5%). Kaplan-Meier survival function suggested 93% cumulative 12-year retention. Cumulative healed rates declined from 91% at 6 months to 77% at 3 years. The healed rate was significantly lower for maxillary teeth without preoperative periapical radiolucency, replanted in more than 15 minutes, and root-end filled with ProRoot MTA. Cox regression identified extraoral time ≤15 minutes as predictor of complication-free healing (P <.04; hazard ratio, 2.767; 95% confidence interval, 1.053-7.272). Conclusions This prospective cohort study of contemporary intentional replantation suggested a cumulative 12-year retention rate of 93% and healed rate of 77% after 3 years. Healing occurred 1.7 times more frequently in teeth replanted within 15 minutes. Although most complications occurred within 1 year after replantation, follow-up should extend for at least 3 years to capture late complications.

AB - Introduction Intentional replantation is an alternative to tooth extraction and prosthetic replacement when conventional endodontic treatment modalities are unfeasible or contraindicated. This study assessed tooth retention and healing after intentional replantation and explored predictors of these outcomes. Methods Data of intentional replantation procedures performed between March 2000 and December 2010 were collected prospectively, excluding teeth with preoperative periodontal and root defects. A cohort of 159 teeth was followed up for 0.5-12 years. Retention and healed status without complications (periapical radiolucency, external root resorption, ankylosis, signs/symptoms, probing ≥6 mm) was recorded and analyzed with Kaplan-Meier survival analysis and Cox proportional hazard regression model (P <.05). Results Complications leading to extraction occurred in 8 of 159 teeth (5%). Kaplan-Meier survival function suggested 93% cumulative 12-year retention. Cumulative healed rates declined from 91% at 6 months to 77% at 3 years. The healed rate was significantly lower for maxillary teeth without preoperative periapical radiolucency, replanted in more than 15 minutes, and root-end filled with ProRoot MTA. Cox regression identified extraoral time ≤15 minutes as predictor of complication-free healing (P <.04; hazard ratio, 2.767; 95% confidence interval, 1.053-7.272). Conclusions This prospective cohort study of contemporary intentional replantation suggested a cumulative 12-year retention rate of 93% and healed rate of 77% after 3 years. Healing occurred 1.7 times more frequently in teeth replanted within 15 minutes. Although most complications occurred within 1 year after replantation, follow-up should extend for at least 3 years to capture late complications.

UR - http://www.scopus.com/inward/record.url?scp=84963546210&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84963546210&partnerID=8YFLogxK

U2 - 10.1016/j.joen.2016.03.006

DO - 10.1016/j.joen.2016.03.006

M3 - Article

VL - 42

SP - 909

EP - 915

JO - Journal of Endodontics

JF - Journal of Endodontics

SN - 0099-2399

IS - 6

ER -