Revascularization-associated Intracanal Calcification: Assessment of Prevalence and Contributing Factors

Minju Song, Yangpei Cao, Su Jung Shin, Won Jun Shon, Nadia Chugal, Reuben H. Kim, Euiseong Kim, Mo K. Kang

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47 Citations (Scopus)


Introduction Intracanal calcifications have been reported in endodontic cases after revascularization. The purpose of the current study was to determine the incidence of intracanal calcification and potential contributing factors in retrospective revascularization cases. Methods Among 37 patients who had undergone revascularization between 2010 and 2014, 29 cases were assessed with average follow-up period of 24.9 months. Clinical and radiographic examinations were performed to evaluate the treatment outcomes, eg, resolution of apical periodontitis (AP), root development, and occurrence of intracanal calcification. Radiographic assessment revealed varied calcification patterns, which were classified into calcific barrier or canal obliteration, collectively referred to as revascularization-associated intracanal calcification (RAIC). Results All 29 cases demonstrated resolution of AP, whereas continued root development with apical closure occurred in 23 of 29 cases (79.3%). RAIC was noted in 18 of 29 cases (62.1%), among which 5 of 18 cases (27.8%) were classified as calcific barrier and 13 of 18 cases as canal obliteration (72.2%). Higher frequency of RAIC was noted in the cases with induced bleeding (16 of 23 cases, 69.6%), whereas the 6 cases without induced bleeding showed RAIC at 33.4%. Also, RAIC occurred more frequently in cases medicated with Ca(OH)2 (10 of 13 cases, 76.9%) than in those medicated with antibiotic pastes (6 of 13 cases, 46.2%). Conclusions This study indicated that RAIC is common (62.1%) among cases treated with revascularization. Multiple contributing factors may include the type of medicaments and induction of intracanal bleeding. Although RAIC does not interfere with resolution of AP, some cases may progress to complete obliteration of root canals and would impede normal function of dental pulp tissues.

Original languageEnglish
Pages (from-to)2025-2033
Number of pages9
JournalJournal of endodontics
Issue number12
Publication statusPublished - 2017 Dec

Bibliographical note

Funding Information:
The authors thank Dr Sunmi Jang (case #1) and Dr Sooyun Kim (case #10) for processing the radiographic images. This study was supported in part by grants from the American Association of Endodontists Foundation (AAEF). M.K.K. is supported by Jack Weichman Endowed fund. The authors deny any conflicts of interest related to this study.

Publisher Copyright:
© 2017 American Association of Endodontists

All Science Journal Classification (ASJC) codes

  • Dentistry(all)


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