A new rhodamine fluorescent probe for monitoring OH has been developed based on the oxidative C–H abstraction reaction of rhodamine cyclic hydrazide. The probe exhibits excellent selectivity for OH with virtually no interference by other ROS/RNS species. Fluorescent imaging of A549 and RAW264.7 cells is also successfully demonstrated to detect intracellular OH in live cells.
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry