Abstract
There are several reports to demonstrate that rifampicin, a major anti-tuberculosis agent, is associated with some adverse renal effects, with a few cases of rifampicin-induced minimal change disease (MCD). In the present case, a 68-year-old female presented with nausea, vomiting, foamy urine, general weakness and edema. She had been taking rifampicin for 4 weeks due to pleural tuberculosis. The patient had no proteinuria before the anti-tuberculosis agents were started, but urine tests upon admission showed heavy proteinuria with a 24-h urinary protein of 9.2 g/day, and serum creatinine, albumin, and total cholesterol levels were 1.36 mg/dL, 2.40 g/dL, and 283 mg/dL, respectively. MCD was diagnosed, and the patient achieved complete remission after cessation of rifampicin without undergoing steroid therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 582-585 |
| Number of pages | 4 |
| Journal | Yonsei medical journal |
| Volume | 56 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2015 Jan 1 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Rifampicin-induced minimal change disease is improved after cessation of rifampicin without steroid therapy. / Park, Dong Hyuk; Lee, Sul A.; Jeong, Hyeon Joo; Yoo, TaeHyun; Kang, Shin-Wook; Oh, Hyung Jung.
In: Yonsei medical journal, Vol. 56, No. 2, 01.01.2015, p. 582-585.Research output: Contribution to journal › Article
TY - JOUR
T1 - Rifampicin-induced minimal change disease is improved after cessation of rifampicin without steroid therapy
AU - Park, Dong Hyuk
AU - Lee, Sul A.
AU - Jeong, Hyeon Joo
AU - Yoo, TaeHyun
AU - Kang, Shin-Wook
AU - Oh, Hyung Jung
PY - 2015/1/1
Y1 - 2015/1/1
N2 - There are several reports to demonstrate that rifampicin, a major anti-tuberculosis agent, is associated with some adverse renal effects, with a few cases of rifampicin-induced minimal change disease (MCD). In the present case, a 68-year-old female presented with nausea, vomiting, foamy urine, general weakness and edema. She had been taking rifampicin for 4 weeks due to pleural tuberculosis. The patient had no proteinuria before the anti-tuberculosis agents were started, but urine tests upon admission showed heavy proteinuria with a 24-h urinary protein of 9.2 g/day, and serum creatinine, albumin, and total cholesterol levels were 1.36 mg/dL, 2.40 g/dL, and 283 mg/dL, respectively. MCD was diagnosed, and the patient achieved complete remission after cessation of rifampicin without undergoing steroid therapy.
AB - There are several reports to demonstrate that rifampicin, a major anti-tuberculosis agent, is associated with some adverse renal effects, with a few cases of rifampicin-induced minimal change disease (MCD). In the present case, a 68-year-old female presented with nausea, vomiting, foamy urine, general weakness and edema. She had been taking rifampicin for 4 weeks due to pleural tuberculosis. The patient had no proteinuria before the anti-tuberculosis agents were started, but urine tests upon admission showed heavy proteinuria with a 24-h urinary protein of 9.2 g/day, and serum creatinine, albumin, and total cholesterol levels were 1.36 mg/dL, 2.40 g/dL, and 283 mg/dL, respectively. MCD was diagnosed, and the patient achieved complete remission after cessation of rifampicin without undergoing steroid therapy.
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UR - http://www.scopus.com/inward/citedby.url?scp=84922803888&partnerID=8YFLogxK
U2 - 10.3349/ymj.2015.56.2.582
DO - 10.3349/ymj.2015.56.2.582
M3 - Article
C2 - 25684013
AN - SCOPUS:84922803888
VL - 56
SP - 582
EP - 585
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 2
ER -