Rifamycin B. oxidase from Monocillium spp., a new type of diphenol oxidase

Moon H. Han, Baik Lin Seong, Hyeung Jin Son, Mheen Tae-Ick

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

It was found that enzyme from a microbial strain, Monocillium spp. ATCC 20621, catalyzed the oxidative reaction of rifamycin B to form rifamycin O. The identification of the reaction products suggested that the reaction proceeded by the oxidative cyclization of rifamycin B to give rifamycin O, which spontaneously hydrolyzed to rifamycin S in neutral aqueous milieu. The characteristic of the enzyme was different as compared with that of other polyphenol oxidases such as laccase. It is proposed that this new type of enzyme be classified into a subgroup EC 1.10.3.6 with a trival name rifamycin B oxidase.

Original languageEnglish
Pages (from-to)36-40
Number of pages5
JournalFEBS Letters
Volume151
Issue number1
DOIs
Publication statusPublished - 1983 Jan 10

Fingerprint

Catechol Oxidase
Enzymes
Laccase
Cyclization
Reaction products
Names
rifamycin B oxidase
rifamycin B
rifamycin O

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Han, Moon H. ; Seong, Baik Lin ; Son, Hyeung Jin ; Tae-Ick, Mheen. / Rifamycin B. oxidase from Monocillium spp., a new type of diphenol oxidase. In: FEBS Letters. 1983 ; Vol. 151, No. 1. pp. 36-40.
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Rifamycin B. oxidase from Monocillium spp., a new type of diphenol oxidase. / Han, Moon H.; Seong, Baik Lin; Son, Hyeung Jin; Tae-Ick, Mheen.

In: FEBS Letters, Vol. 151, No. 1, 10.01.1983, p. 36-40.

Research output: Contribution to journalArticle

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