Risk factors for recurrent high-risk polyps after the removal of high-risk polyps at initial colonoscopy

Hui Won Jang, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Won Ho Kim, Tae Il Kim

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: Colonoscopic polypectomy and surveillance are important to prevent colorectal cancer and identify additional relative risk factors for adequate surveillance. In this study, we evaluated risk factors related to recurrent high-risk polyps during the surveillance of patients with high-risk polyps. Materials and Methods: We included 434 patients who had high-risk polyps (adenoma ≥10 mm, ≥3 adenomas, villous histology, or high-grade dysplasia) on the baseline colonoscopy and underwent at least one surveillance colonoscopy from 2005 to 2011 at Severance Hospital. Data regarding patient characteristics, bowel preparation and polyp size, location, number, and pathological diagnosis were retrospectively collected from medical records. Patients with recurrent high-risk polyps were compared with patients with low-risk or no polyps during surveillance. Results: Patients were predominantly male (77.4%), with a mean age of 61.0±8.6 years and mean follow-up of 1.5±0.8 years. Highrisk polyps recurred during surveillance colonoscopy in 51 (11.8%) patients. Results of multivariate analysis showed that male gender, poor bowel preparation, and a larger number of adenomas were independent risk factors for recurrent high-risk polyps (p=0.047, 0.01, and <0.001, respectively). Compared with high-risk polyps found during initial colonoscopy, high-risk polyps on surveillance colonoscopy had higher proportions of small adenomas, low-risk pathology, and fewer adenomas overall, but there was no difference in location. Conclusion: Male patients and those with poor bowel preparation for colonoscopy or higher numbers of adenomas were more likely to experience recurrent high-risk polyps.

Original languageEnglish
Pages (from-to)1559-1565
Number of pages7
JournalYonsei medical journal
Volume56
Issue number6
DOIs
Publication statusPublished - 2015 Nov

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Colonoscopy
Polyps
Adenoma
Villous Adenoma
Medical Records
Colorectal Neoplasms
Histology
Multivariate Analysis
Pathology

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Jang, Hui Won ; Park, Soo Jung ; Hong, Sung Pil ; Cheon, Jae Hee ; Kim, Won Ho ; Kim, Tae Il. / Risk factors for recurrent high-risk polyps after the removal of high-risk polyps at initial colonoscopy. In: Yonsei medical journal. 2015 ; Vol. 56, No. 6. pp. 1559-1565.
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abstract = "Purpose: Colonoscopic polypectomy and surveillance are important to prevent colorectal cancer and identify additional relative risk factors for adequate surveillance. In this study, we evaluated risk factors related to recurrent high-risk polyps during the surveillance of patients with high-risk polyps. Materials and Methods: We included 434 patients who had high-risk polyps (adenoma ≥10 mm, ≥3 adenomas, villous histology, or high-grade dysplasia) on the baseline colonoscopy and underwent at least one surveillance colonoscopy from 2005 to 2011 at Severance Hospital. Data regarding patient characteristics, bowel preparation and polyp size, location, number, and pathological diagnosis were retrospectively collected from medical records. Patients with recurrent high-risk polyps were compared with patients with low-risk or no polyps during surveillance. Results: Patients were predominantly male (77.4{\%}), with a mean age of 61.0±8.6 years and mean follow-up of 1.5±0.8 years. Highrisk polyps recurred during surveillance colonoscopy in 51 (11.8{\%}) patients. Results of multivariate analysis showed that male gender, poor bowel preparation, and a larger number of adenomas were independent risk factors for recurrent high-risk polyps (p=0.047, 0.01, and <0.001, respectively). Compared with high-risk polyps found during initial colonoscopy, high-risk polyps on surveillance colonoscopy had higher proportions of small adenomas, low-risk pathology, and fewer adenomas overall, but there was no difference in location. Conclusion: Male patients and those with poor bowel preparation for colonoscopy or higher numbers of adenomas were more likely to experience recurrent high-risk polyps.",
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Risk factors for recurrent high-risk polyps after the removal of high-risk polyps at initial colonoscopy. / Jang, Hui Won; Park, Soo Jung; Hong, Sung Pil; Cheon, Jae Hee; Kim, Won Ho; Kim, Tae Il.

In: Yonsei medical journal, Vol. 56, No. 6, 11.2015, p. 1559-1565.

Research output: Contribution to journalArticle

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AU - Jang, Hui Won

AU - Park, Soo Jung

AU - Hong, Sung Pil

AU - Cheon, Jae Hee

AU - Kim, Won Ho

AU - Kim, Tae Il

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N2 - Purpose: Colonoscopic polypectomy and surveillance are important to prevent colorectal cancer and identify additional relative risk factors for adequate surveillance. In this study, we evaluated risk factors related to recurrent high-risk polyps during the surveillance of patients with high-risk polyps. Materials and Methods: We included 434 patients who had high-risk polyps (adenoma ≥10 mm, ≥3 adenomas, villous histology, or high-grade dysplasia) on the baseline colonoscopy and underwent at least one surveillance colonoscopy from 2005 to 2011 at Severance Hospital. Data regarding patient characteristics, bowel preparation and polyp size, location, number, and pathological diagnosis were retrospectively collected from medical records. Patients with recurrent high-risk polyps were compared with patients with low-risk or no polyps during surveillance. Results: Patients were predominantly male (77.4%), with a mean age of 61.0±8.6 years and mean follow-up of 1.5±0.8 years. Highrisk polyps recurred during surveillance colonoscopy in 51 (11.8%) patients. Results of multivariate analysis showed that male gender, poor bowel preparation, and a larger number of adenomas were independent risk factors for recurrent high-risk polyps (p=0.047, 0.01, and <0.001, respectively). Compared with high-risk polyps found during initial colonoscopy, high-risk polyps on surveillance colonoscopy had higher proportions of small adenomas, low-risk pathology, and fewer adenomas overall, but there was no difference in location. Conclusion: Male patients and those with poor bowel preparation for colonoscopy or higher numbers of adenomas were more likely to experience recurrent high-risk polyps.

AB - Purpose: Colonoscopic polypectomy and surveillance are important to prevent colorectal cancer and identify additional relative risk factors for adequate surveillance. In this study, we evaluated risk factors related to recurrent high-risk polyps during the surveillance of patients with high-risk polyps. Materials and Methods: We included 434 patients who had high-risk polyps (adenoma ≥10 mm, ≥3 adenomas, villous histology, or high-grade dysplasia) on the baseline colonoscopy and underwent at least one surveillance colonoscopy from 2005 to 2011 at Severance Hospital. Data regarding patient characteristics, bowel preparation and polyp size, location, number, and pathological diagnosis were retrospectively collected from medical records. Patients with recurrent high-risk polyps were compared with patients with low-risk or no polyps during surveillance. Results: Patients were predominantly male (77.4%), with a mean age of 61.0±8.6 years and mean follow-up of 1.5±0.8 years. Highrisk polyps recurred during surveillance colonoscopy in 51 (11.8%) patients. Results of multivariate analysis showed that male gender, poor bowel preparation, and a larger number of adenomas were independent risk factors for recurrent high-risk polyps (p=0.047, 0.01, and <0.001, respectively). Compared with high-risk polyps found during initial colonoscopy, high-risk polyps on surveillance colonoscopy had higher proportions of small adenomas, low-risk pathology, and fewer adenomas overall, but there was no difference in location. Conclusion: Male patients and those with poor bowel preparation for colonoscopy or higher numbers of adenomas were more likely to experience recurrent high-risk polyps.

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