Abstract
Purpose: Colonoscopic polypectomy and surveillance are important to prevent colorectal cancer and identify additional relative risk factors for adequate surveillance. In this study, we evaluated risk factors related to recurrent high-risk polyps during the surveillance of patients with high-risk polyps. Materials and Methods: We included 434 patients who had high-risk polyps (adenoma ≥10 mm, ≥3 adenomas, villous histology, or high-grade dysplasia) on the baseline colonoscopy and underwent at least one surveillance colonoscopy from 2005 to 2011 at Severance Hospital. Data regarding patient characteristics, bowel preparation and polyp size, location, number, and pathological diagnosis were retrospectively collected from medical records. Patients with recurrent high-risk polyps were compared with patients with low-risk or no polyps during surveillance. Results: Patients were predominantly male (77.4%), with a mean age of 61.0±8.6 years and mean follow-up of 1.5±0.8 years. Highrisk polyps recurred during surveillance colonoscopy in 51 (11.8%) patients. Results of multivariate analysis showed that male gender, poor bowel preparation, and a larger number of adenomas were independent risk factors for recurrent high-risk polyps (p=0.047, 0.01, and <0.001, respectively). Compared with high-risk polyps found during initial colonoscopy, high-risk polyps on surveillance colonoscopy had higher proportions of small adenomas, low-risk pathology, and fewer adenomas overall, but there was no difference in location. Conclusion: Male patients and those with poor bowel preparation for colonoscopy or higher numbers of adenomas were more likely to experience recurrent high-risk polyps.
| Original language | English |
|---|---|
| Pages (from-to) | 1559-1565 |
| Number of pages | 7 |
| Journal | Yonsei medical journal |
| Volume | 56 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2015 Nov |
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- Medicine(all)
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Risk factors for recurrent high-risk polyps after the removal of high-risk polyps at initial colonoscopy. / Jang, Hui Won; Park, Soo Jung; Hong, Sung Pil; Cheon, Jae Hee; Kim, Won Ho; Kim, Tae Il.
In: Yonsei medical journal, Vol. 56, No. 6, 11.2015, p. 1559-1565.Research output: Contribution to journal › Article
TY - JOUR
T1 - Risk factors for recurrent high-risk polyps after the removal of high-risk polyps at initial colonoscopy
AU - Jang, Hui Won
AU - Park, Soo Jung
AU - Hong, Sung Pil
AU - Cheon, Jae Hee
AU - Kim, Won Ho
AU - Kim, Tae Il
PY - 2015/11
Y1 - 2015/11
N2 - Purpose: Colonoscopic polypectomy and surveillance are important to prevent colorectal cancer and identify additional relative risk factors for adequate surveillance. In this study, we evaluated risk factors related to recurrent high-risk polyps during the surveillance of patients with high-risk polyps. Materials and Methods: We included 434 patients who had high-risk polyps (adenoma ≥10 mm, ≥3 adenomas, villous histology, or high-grade dysplasia) on the baseline colonoscopy and underwent at least one surveillance colonoscopy from 2005 to 2011 at Severance Hospital. Data regarding patient characteristics, bowel preparation and polyp size, location, number, and pathological diagnosis were retrospectively collected from medical records. Patients with recurrent high-risk polyps were compared with patients with low-risk or no polyps during surveillance. Results: Patients were predominantly male (77.4%), with a mean age of 61.0±8.6 years and mean follow-up of 1.5±0.8 years. Highrisk polyps recurred during surveillance colonoscopy in 51 (11.8%) patients. Results of multivariate analysis showed that male gender, poor bowel preparation, and a larger number of adenomas were independent risk factors for recurrent high-risk polyps (p=0.047, 0.01, and <0.001, respectively). Compared with high-risk polyps found during initial colonoscopy, high-risk polyps on surveillance colonoscopy had higher proportions of small adenomas, low-risk pathology, and fewer adenomas overall, but there was no difference in location. Conclusion: Male patients and those with poor bowel preparation for colonoscopy or higher numbers of adenomas were more likely to experience recurrent high-risk polyps.
AB - Purpose: Colonoscopic polypectomy and surveillance are important to prevent colorectal cancer and identify additional relative risk factors for adequate surveillance. In this study, we evaluated risk factors related to recurrent high-risk polyps during the surveillance of patients with high-risk polyps. Materials and Methods: We included 434 patients who had high-risk polyps (adenoma ≥10 mm, ≥3 adenomas, villous histology, or high-grade dysplasia) on the baseline colonoscopy and underwent at least one surveillance colonoscopy from 2005 to 2011 at Severance Hospital. Data regarding patient characteristics, bowel preparation and polyp size, location, number, and pathological diagnosis were retrospectively collected from medical records. Patients with recurrent high-risk polyps were compared with patients with low-risk or no polyps during surveillance. Results: Patients were predominantly male (77.4%), with a mean age of 61.0±8.6 years and mean follow-up of 1.5±0.8 years. Highrisk polyps recurred during surveillance colonoscopy in 51 (11.8%) patients. Results of multivariate analysis showed that male gender, poor bowel preparation, and a larger number of adenomas were independent risk factors for recurrent high-risk polyps (p=0.047, 0.01, and <0.001, respectively). Compared with high-risk polyps found during initial colonoscopy, high-risk polyps on surveillance colonoscopy had higher proportions of small adenomas, low-risk pathology, and fewer adenomas overall, but there was no difference in location. Conclusion: Male patients and those with poor bowel preparation for colonoscopy or higher numbers of adenomas were more likely to experience recurrent high-risk polyps.
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U2 - 10.3349/ymj.2015.56.6.1559
DO - 10.3349/ymj.2015.56.6.1559
M3 - Article
C2 - 26446637
AN - SCOPUS:84944128603
VL - 56
SP - 1559
EP - 1565
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 6
ER -