Risk factors for tuberculosis after gastrectomy in gastric cancer

Won Jai Jung, Young Mok Park, Joo Han Song, Kyung Soo Chung, Song Yee Kim, Eun Young Kim, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Sung Hoon Noh, Ji Yeong An, Young Ae Kang

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

AIM: To examine incidence of tuberculosis (TB) in gastrectomy patients and investigate the risk factors for developing TB after gastrectomy in patients with gastric cancer. METHODS: A retrospective cohort study of gastrectomy patients with gastric cancer was performed at a university-affiliated hospital in Seoul, South Korea between January 2007 and December 2009. We reviewed patient medical records and collected data associated with the risk of TB, surgery, and gastric cancer. Standardized incidence ratios (SIRs) of TB were calculated to compare the incidence of TB in gastrectomy patients with that in the general Korean population, and risk factors for TB after gastrectomies were analyzed. RESULTS: Among the 1776 gastrectomy patients, 0.9% (16/1776) developed post-gastrectomy TB, with an incidence of 223.7 cases per 100000 patients per year. The overall incidence of TB in gastrectomy patients, adjusted by sex and age, was significantly higher than that in the general population (SIR = 2.22, 95%CI: 1.27-3.60). Previous TB infection [odds ratio (OR) = 7.1, P < 0.001], lower body mass index (BMI) (kg/m2; OR = 1.21, P = 0.043) and gastrectomy extent (total gastrectomy vs subtotal gastrectomy) (OR = 3.48, P = 0.017) were significant risk factors for TB after gastrectomy in a multivariate analysis. CONCLUSION: TB incidence after gastrectomy is higher than that in the general population. Previous TB infection, lower BMI, and total gastrectomy are risk factors for TB after gastrectomy in patients with gastric cancer.

Original languageEnglish
Pages (from-to)2585-2591
Number of pages7
JournalWorld Journal of Gastroenterology
Volume22
Issue number8
DOIs
Publication statusPublished - 2016 Feb 28

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Gastrectomy
Stomach Neoplasms
Tuberculosis
Incidence
Odds Ratio
Body Mass Index
Population
Republic of Korea
Infection
Medical Records
Cohort Studies

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Jung, W. J., Park, Y. M., Song, J. H., Chung, K. S., Kim, S. Y., Kim, E. Y., ... Kang, Y. A. (2016). Risk factors for tuberculosis after gastrectomy in gastric cancer. World Journal of Gastroenterology, 22(8), 2585-2591. https://doi.org/10.3748/wjg.v22.i8.2585
Jung, Won Jai ; Park, Young Mok ; Song, Joo Han ; Chung, Kyung Soo ; Kim, Song Yee ; Kim, Eun Young ; Jung, Ji Ye ; Park, Moo Suk ; Kim, Young Sam ; Kim, Se Kyu ; Chang, Joon ; Noh, Sung Hoon ; An, Ji Yeong ; Kang, Young Ae. / Risk factors for tuberculosis after gastrectomy in gastric cancer. In: World Journal of Gastroenterology. 2016 ; Vol. 22, No. 8. pp. 2585-2591.
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title = "Risk factors for tuberculosis after gastrectomy in gastric cancer",
abstract = "AIM: To examine incidence of tuberculosis (TB) in gastrectomy patients and investigate the risk factors for developing TB after gastrectomy in patients with gastric cancer. METHODS: A retrospective cohort study of gastrectomy patients with gastric cancer was performed at a university-affiliated hospital in Seoul, South Korea between January 2007 and December 2009. We reviewed patient medical records and collected data associated with the risk of TB, surgery, and gastric cancer. Standardized incidence ratios (SIRs) of TB were calculated to compare the incidence of TB in gastrectomy patients with that in the general Korean population, and risk factors for TB after gastrectomies were analyzed. RESULTS: Among the 1776 gastrectomy patients, 0.9{\%} (16/1776) developed post-gastrectomy TB, with an incidence of 223.7 cases per 100000 patients per year. The overall incidence of TB in gastrectomy patients, adjusted by sex and age, was significantly higher than that in the general population (SIR = 2.22, 95{\%}CI: 1.27-3.60). Previous TB infection [odds ratio (OR) = 7.1, P < 0.001], lower body mass index (BMI) (kg/m2; OR = 1.21, P = 0.043) and gastrectomy extent (total gastrectomy vs subtotal gastrectomy) (OR = 3.48, P = 0.017) were significant risk factors for TB after gastrectomy in a multivariate analysis. CONCLUSION: TB incidence after gastrectomy is higher than that in the general population. Previous TB infection, lower BMI, and total gastrectomy are risk factors for TB after gastrectomy in patients with gastric cancer.",
author = "Jung, {Won Jai} and Park, {Young Mok} and Song, {Joo Han} and Chung, {Kyung Soo} and Kim, {Song Yee} and Kim, {Eun Young} and Jung, {Ji Ye} and Park, {Moo Suk} and Kim, {Young Sam} and Kim, {Se Kyu} and Joon Chang and Noh, {Sung Hoon} and An, {Ji Yeong} and Kang, {Young Ae}",
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Jung, WJ, Park, YM, Song, JH, Chung, KS, Kim, SY, Kim, EY, Jung, JY, Park, MS, Kim, YS, Kim, SK, Chang, J, Noh, SH, An, JY & Kang, YA 2016, 'Risk factors for tuberculosis after gastrectomy in gastric cancer', World Journal of Gastroenterology, vol. 22, no. 8, pp. 2585-2591. https://doi.org/10.3748/wjg.v22.i8.2585

Risk factors for tuberculosis after gastrectomy in gastric cancer. / Jung, Won Jai; Park, Young Mok; Song, Joo Han; Chung, Kyung Soo; Kim, Song Yee; Kim, Eun Young; Jung, Ji Ye; Park, Moo Suk; Kim, Young Sam; Kim, Se Kyu; Chang, Joon; Noh, Sung Hoon; An, Ji Yeong; Kang, Young Ae.

In: World Journal of Gastroenterology, Vol. 22, No. 8, 28.02.2016, p. 2585-2591.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Risk factors for tuberculosis after gastrectomy in gastric cancer

AU - Jung, Won Jai

AU - Park, Young Mok

AU - Song, Joo Han

AU - Chung, Kyung Soo

AU - Kim, Song Yee

AU - Kim, Eun Young

AU - Jung, Ji Ye

AU - Park, Moo Suk

AU - Kim, Young Sam

AU - Kim, Se Kyu

AU - Chang, Joon

AU - Noh, Sung Hoon

AU - An, Ji Yeong

AU - Kang, Young Ae

PY - 2016/2/28

Y1 - 2016/2/28

N2 - AIM: To examine incidence of tuberculosis (TB) in gastrectomy patients and investigate the risk factors for developing TB after gastrectomy in patients with gastric cancer. METHODS: A retrospective cohort study of gastrectomy patients with gastric cancer was performed at a university-affiliated hospital in Seoul, South Korea between January 2007 and December 2009. We reviewed patient medical records and collected data associated with the risk of TB, surgery, and gastric cancer. Standardized incidence ratios (SIRs) of TB were calculated to compare the incidence of TB in gastrectomy patients with that in the general Korean population, and risk factors for TB after gastrectomies were analyzed. RESULTS: Among the 1776 gastrectomy patients, 0.9% (16/1776) developed post-gastrectomy TB, with an incidence of 223.7 cases per 100000 patients per year. The overall incidence of TB in gastrectomy patients, adjusted by sex and age, was significantly higher than that in the general population (SIR = 2.22, 95%CI: 1.27-3.60). Previous TB infection [odds ratio (OR) = 7.1, P < 0.001], lower body mass index (BMI) (kg/m2; OR = 1.21, P = 0.043) and gastrectomy extent (total gastrectomy vs subtotal gastrectomy) (OR = 3.48, P = 0.017) were significant risk factors for TB after gastrectomy in a multivariate analysis. CONCLUSION: TB incidence after gastrectomy is higher than that in the general population. Previous TB infection, lower BMI, and total gastrectomy are risk factors for TB after gastrectomy in patients with gastric cancer.

AB - AIM: To examine incidence of tuberculosis (TB) in gastrectomy patients and investigate the risk factors for developing TB after gastrectomy in patients with gastric cancer. METHODS: A retrospective cohort study of gastrectomy patients with gastric cancer was performed at a university-affiliated hospital in Seoul, South Korea between January 2007 and December 2009. We reviewed patient medical records and collected data associated with the risk of TB, surgery, and gastric cancer. Standardized incidence ratios (SIRs) of TB were calculated to compare the incidence of TB in gastrectomy patients with that in the general Korean population, and risk factors for TB after gastrectomies were analyzed. RESULTS: Among the 1776 gastrectomy patients, 0.9% (16/1776) developed post-gastrectomy TB, with an incidence of 223.7 cases per 100000 patients per year. The overall incidence of TB in gastrectomy patients, adjusted by sex and age, was significantly higher than that in the general population (SIR = 2.22, 95%CI: 1.27-3.60). Previous TB infection [odds ratio (OR) = 7.1, P < 0.001], lower body mass index (BMI) (kg/m2; OR = 1.21, P = 0.043) and gastrectomy extent (total gastrectomy vs subtotal gastrectomy) (OR = 3.48, P = 0.017) were significant risk factors for TB after gastrectomy in a multivariate analysis. CONCLUSION: TB incidence after gastrectomy is higher than that in the general population. Previous TB infection, lower BMI, and total gastrectomy are risk factors for TB after gastrectomy in patients with gastric cancer.

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Jung WJ, Park YM, Song JH, Chung KS, Kim SY, Kim EY et al. Risk factors for tuberculosis after gastrectomy in gastric cancer. World Journal of Gastroenterology. 2016 Feb 28;22(8):2585-2591. https://doi.org/10.3748/wjg.v22.i8.2585