Risk factors for vitamin D inadequacy among women with osteoporosis: An international epidemiological study

R. Rizzole, J. A. Eisman, J. Norquist, Ö Ljunggren, G. Krishnarajah, S. K. Lim, Julie Chandler

Research output: Contribution to journalReview article

54 Citations (Scopus)

Abstract

A serum 25-hydroxyvitamin D [25(OH)D] level of 75 nmol/l (30 ng/ml) has been proposed as the minimum for adequate vitamin D nutrition as lower levels are associated with increases in serum parathyroid hormone in otherwise healthy adults. Amongst 2589 community-dwelling, postmenopausal women with osteoporosis from 18 countries, recruited to determine risk factors for vitamin D inadequacy, 64% had vitamin D inadequacy. General health, education, ethnicity, sun exposure, skin reactivity, diet, recent travel to sunny climates, vitamin D supplementation, body mass index (BMI), season and latitude were assessed using logistic regression models. Asian ethnicity, BMI ≥30 kg/m2, living in non-equatorial countries, inadequate vitamin D supplementation, poor/fair health, no education about vitamin D, skin reactivity and no recent travel to sunny areas were significant predictors. Several modifiable risk factors are associated with vitamin D inadequacy worldwide, suggesting potentially simple ways to increase vitamin D and improve bone health in postmenopausal women.

Original languageEnglish
Pages (from-to)1013-1019
Number of pages7
JournalInternational Journal of Clinical Practice
Volume60
Issue number8
DOIs
Publication statusPublished - 2006 Aug 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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