Risks of Being Malignant or High Risk and Their Characteristics in Breast Lesions 20 mm or Larger after Benign Results on Ultrasonography-Guided 14-Gauge Core Needle Biopsy

Hee Jung Moon, minjung Kim, Jung Hyun Yoon, Eunkyung Kim

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Abstract

Purpose The malignancy risk, risk of being high-risk lesions after benign results on ultrasonography-guided 14-gauge core needle biopsies (US-CNBs), and their characteristics in breast lesions of 20 mm or greater were investigated. Methods Eight hundred forty-seven breast lesions with benign results on US-CNB were classified as benign, high risk, and malignant through excision and clinical follow-up. The risks of being malignant or high risk were analyzed in all lesions, lesions 20 to 29 mm, and lesions 30 mm or greater. Their clinicopathological characteristics were evaluated. Results Of 847, 18 (2.1%) were malignant, 53 (6.3%) were high-risk lesions, and 776 (91.6%) were benign. Of 18 malignancies, 6 (33.3%) were malignant phyllodes tumors and 12 (66.7%) were carcinomas. In benign lesions 20 to 29 mm, risks of being malignant or high risk were 1.6% (9 of 566) and 4.4% (25 of 566). In 281 lesions 30 mm or greater, the risks of being malignant or high risk were 3.2% and 10%. The risk of being high risk in lesions 30 mm or greater was 10%, significantly higher than 4.4% of lesions 20 to 29 mm (P = 0.002). Conclusions Excision can be considered in lesions measuring 20 mm or larger because of the 2.1% malignancy risk and the 6.3% risk of being high-risk lesions despite benign results on US-CNB. Excision should be considered in lesions measuring 30 mm or larger because of the 3.2% malignancy risk and the 10% risk of being high-risk lesions.

Original languageEnglish
Pages (from-to)157-163
Number of pages7
JournalUltrasound Quarterly
Volume32
Issue number2
DOIs
Publication statusPublished - 2016 Jun 1

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Large-Core Needle Biopsy
Ultrasonography
Breast
Neoplasms
Phyllodes Tumor

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

@article{c10ecb72e3e449a7b394cf4a9cc7759f,
title = "Risks of Being Malignant or High Risk and Their Characteristics in Breast Lesions 20 mm or Larger after Benign Results on Ultrasonography-Guided 14-Gauge Core Needle Biopsy",
abstract = "Purpose The malignancy risk, risk of being high-risk lesions after benign results on ultrasonography-guided 14-gauge core needle biopsies (US-CNBs), and their characteristics in breast lesions of 20 mm or greater were investigated. Methods Eight hundred forty-seven breast lesions with benign results on US-CNB were classified as benign, high risk, and malignant through excision and clinical follow-up. The risks of being malignant or high risk were analyzed in all lesions, lesions 20 to 29 mm, and lesions 30 mm or greater. Their clinicopathological characteristics were evaluated. Results Of 847, 18 (2.1{\%}) were malignant, 53 (6.3{\%}) were high-risk lesions, and 776 (91.6{\%}) were benign. Of 18 malignancies, 6 (33.3{\%}) were malignant phyllodes tumors and 12 (66.7{\%}) were carcinomas. In benign lesions 20 to 29 mm, risks of being malignant or high risk were 1.6{\%} (9 of 566) and 4.4{\%} (25 of 566). In 281 lesions 30 mm or greater, the risks of being malignant or high risk were 3.2{\%} and 10{\%}. The risk of being high risk in lesions 30 mm or greater was 10{\%}, significantly higher than 4.4{\%} of lesions 20 to 29 mm (P = 0.002). Conclusions Excision can be considered in lesions measuring 20 mm or larger because of the 2.1{\%} malignancy risk and the 6.3{\%} risk of being high-risk lesions despite benign results on US-CNB. Excision should be considered in lesions measuring 30 mm or larger because of the 3.2{\%} malignancy risk and the 10{\%} risk of being high-risk lesions.",
author = "Moon, {Hee Jung} and minjung Kim and Yoon, {Jung Hyun} and Eunkyung Kim",
year = "2016",
month = "6",
day = "1",
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language = "English",
volume = "32",
pages = "157--163",
journal = "Ultrasound Quarterly",
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T1 - Risks of Being Malignant or High Risk and Their Characteristics in Breast Lesions 20 mm or Larger after Benign Results on Ultrasonography-Guided 14-Gauge Core Needle Biopsy

AU - Moon, Hee Jung

AU - Kim, minjung

AU - Yoon, Jung Hyun

AU - Kim, Eunkyung

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Purpose The malignancy risk, risk of being high-risk lesions after benign results on ultrasonography-guided 14-gauge core needle biopsies (US-CNBs), and their characteristics in breast lesions of 20 mm or greater were investigated. Methods Eight hundred forty-seven breast lesions with benign results on US-CNB were classified as benign, high risk, and malignant through excision and clinical follow-up. The risks of being malignant or high risk were analyzed in all lesions, lesions 20 to 29 mm, and lesions 30 mm or greater. Their clinicopathological characteristics were evaluated. Results Of 847, 18 (2.1%) were malignant, 53 (6.3%) were high-risk lesions, and 776 (91.6%) were benign. Of 18 malignancies, 6 (33.3%) were malignant phyllodes tumors and 12 (66.7%) were carcinomas. In benign lesions 20 to 29 mm, risks of being malignant or high risk were 1.6% (9 of 566) and 4.4% (25 of 566). In 281 lesions 30 mm or greater, the risks of being malignant or high risk were 3.2% and 10%. The risk of being high risk in lesions 30 mm or greater was 10%, significantly higher than 4.4% of lesions 20 to 29 mm (P = 0.002). Conclusions Excision can be considered in lesions measuring 20 mm or larger because of the 2.1% malignancy risk and the 6.3% risk of being high-risk lesions despite benign results on US-CNB. Excision should be considered in lesions measuring 30 mm or larger because of the 3.2% malignancy risk and the 10% risk of being high-risk lesions.

AB - Purpose The malignancy risk, risk of being high-risk lesions after benign results on ultrasonography-guided 14-gauge core needle biopsies (US-CNBs), and their characteristics in breast lesions of 20 mm or greater were investigated. Methods Eight hundred forty-seven breast lesions with benign results on US-CNB were classified as benign, high risk, and malignant through excision and clinical follow-up. The risks of being malignant or high risk were analyzed in all lesions, lesions 20 to 29 mm, and lesions 30 mm or greater. Their clinicopathological characteristics were evaluated. Results Of 847, 18 (2.1%) were malignant, 53 (6.3%) were high-risk lesions, and 776 (91.6%) were benign. Of 18 malignancies, 6 (33.3%) were malignant phyllodes tumors and 12 (66.7%) were carcinomas. In benign lesions 20 to 29 mm, risks of being malignant or high risk were 1.6% (9 of 566) and 4.4% (25 of 566). In 281 lesions 30 mm or greater, the risks of being malignant or high risk were 3.2% and 10%. The risk of being high risk in lesions 30 mm or greater was 10%, significantly higher than 4.4% of lesions 20 to 29 mm (P = 0.002). Conclusions Excision can be considered in lesions measuring 20 mm or larger because of the 2.1% malignancy risk and the 6.3% risk of being high-risk lesions despite benign results on US-CNB. Excision should be considered in lesions measuring 30 mm or larger because of the 3.2% malignancy risk and the 10% risk of being high-risk lesions.

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U2 - 10.1097/RUQ.0000000000000179

DO - 10.1097/RUQ.0000000000000179

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VL - 32

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JO - Ultrasound Quarterly

JF - Ultrasound Quarterly

SN - 0894-8771

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