Role of the Porphyromonas gingivalis InlJ protein in homotypic and heterotypic biofilm development

Cindy A. Capestany, Masae Kuboniwa, Il Young Jung, Yoonsuk Park, Gena D. Tribble, Richard J. Lamont

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InlJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis- Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InlJ in regulating biofilm accumulations of P. gingivalis.

Original languageEnglish
Pages (from-to)3002-3005
Number of pages4
JournalInfection and Immunity
Volume74
Issue number5
DOIs
Publication statusPublished - 2006 May

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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